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DR.SU METALFE'S COMPANY COULD BE ON THE VERGE OF CURING M.S

Dear friends please read
http://ushealthmagz.com/2018/07/03/meet ... sclerosis/
Dr.Sumetalfe's company LiFNano could be on the verge of curing M.S
Regards
Seeva
Read more : DR.SU METALFE'S COMPANY COULD BE ON THE VERGE OF CURING M.S | Views : 714 | Replies : 3 | Forum : Drug Pipeline


2018 review: MS Patients' Use of Vitamins & Supplements

can't get into full text for this one, so no opportunity to critique as yet:

Use of Vitamins and Dietary Supplements by Patients With Multiple Sclerosis
https://jamanetwork.com/journals/jamane ... ct/2679039

Abstract
Importance Surveys of patients with multiple sclerosis report that most are interested in modifying their diet and using supplements to potentially reduce the severity and symptoms of the disease. This review provides an updated overview of the current state ...
Read more : 2018 review: MS Patients' Use of Vitamins & Supplements | Views : 430 | Replies : 1 | Forum : Natural Approach


Barts blog: EBV in Brain

EBV in Brain

Source: http://multiple-sclerosis-research.blog ... brain.html

The best evidence to date does suggest that EBV is present in both MS and control brains, but is more common in pwMS (90% vs 24%).
Clearly, the presence of EBV-infected B cells in the brain is not sufficient to drive disease activity. Further work needs to be done to understand why some people are perfectly healthy despite having EBV in their ...
Read more : Barts blog: EBV in Brain | Views : 420 | Replies : 0 | Forum : MS Etiology and Pathogenesis


Immunoglobulins and B-cells

It seems that B-cells are responsible for producing the oligoclonal Bands (OCB) that appear in MS. For some reason which I don't understand, the B-cells are clones from the same one and produce mainly three immunoglobins (Ig) in CSF: IgG, IgM and IgA.

http://n.neurology.org/content/90/15_Supplement/P1.394

Cerebrospinal Fluid IgA Levels Correlate with Disease Activity in Patients with Multiple Sclerosis; A Novel Finding (P1.394)
Read more : Immunoglobulins and B-cells | Views : 402 | Replies : 0 | Forum : MS Etiology and Pathogenesis


For the newly diagnosed - from a (sorta) old timer

This post is for the newly diagnosed. I remember being where you are and feeling scared as hell, thinking that my life as I knew it was over. My mother also had MS and it was very severe. She couldn't walk, feed herself, take care of any of her needs, and could barely talk. She was almost bed ridden. She died from MS four years after I was diagnosed. That was 18 years ago.

I ...
Read more : For the newly diagnosed - from a (sorta) old timer | Views : 526 | Replies : 4 | Forum : General Discussion


A promising treatment in immune-related diseases and cancer

2018 Jun 6
Shengjing Hospital of China Medical University, China
Low-dose naltrexone (LDN): A promising treatment in immune-related diseases and cancer therapy. https://www.ncbi.nlm.nih.gov/pubmed/29885638

Naltrexone, a non-selective antagonist of opioid receptors, is mainly used as rehabilitation therapy for discharged opiate addicts to eliminate addiction in order to maintain a normal life and prevent or reduce relapse. In recent years, there have been some novel and significant findings on the off-label ...
Read more : A promising treatment in immune-related diseases and cancer | Views : 594 | Replies : 1 | Forum : Low Dose Naltrexone


FDA approves cannabidiol Epidiolex

FDA approves cannabidiol Epidiolex
https://www.peoplespharmacy.com/2018/06 ... n-for-you/

The Food and Drug Administration recently approved the first drug made from Cannabis sativa. This plant is known more often as marijuana. FDA approval of cannabidiol under the brand name Epidiolex is for treating two nearly intractable types of epilepsy in children. One is called Dravet syndrome, while the other is termed Lennox Gastaut syndrome. These specific syndromes are rare. However, GW ...
Read more : FDA approves cannabidiol Epidiolex | Views : 637 | Replies : 0 | Forum : Medical Marijuana


Another step closer to a blood test

In the Pipeline-Multiple Sclerosis: The Potential of Neurofilament Light Chain as a Biomarker of MS Activity, Progression

https://journals.lww.com/neurotodayonli ... al.12.aspx

Using a novel immunoassay, researchers were able to detect low levels of neurofilament light chain (NfL) in patients with progressive multiple sclerosis (MS). They propose that NfL could be used as a marker of disease progression and response to treatment.

LOS ANGELES — Evidence is growing that neurofilament light ...
Read more : Another step closer to a blood test | Views : 555 | Replies : 0 | Forum : General Discussion


How B-cells produce MS

For most of the authors is not an issue anymore if B-cells are the cause of MS. The question is how they produce MS. Here there is a fully available review.

Reassessing B cell contributions in multiple sclerosis

https://www.nature.com/articles/s41590-018-0135-x

Abstract

There is growing recognition that B cell contributions to normal immune responses extend well beyond their potential to become antibody-producing cells, including roles at the innate–adaptive interface and their ...
Read more : How B-cells produce MS | Views : 501 | Replies : 0 | Forum : MS Etiology and Pathogenesis


MS B-cells in vitro do weird things. CCSVI link?

This is an article that I am reading slowly, as I do not understand most of the things it says. But the summary is that MS B-cells do weird things. Something that was already suspected, because B-cells depletion with anti-CD20 MABs is the best thing we have at this time against MS.

It seems that the researchers have extracted B-cells from MS patients and infected them with the Epstein-Barr virus EBV. After that, it seems ...


 

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