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Discussion of statins (Lipitor, Zocor, etc.) in the treatment of MS.

No Benefit of Simvastatin

Read more : No Benefit of Simvastatin | Views : 2012 | Replies : 1


Statins have detrimental effects on remyelination in MS

Image

Simvastatin interferes with process outgrowth and branching of oligodendrocytes.

Abstract

Statins have attracted interest as a treatment option for multiple sclerosis (MS) because of their pleiotropic antiinflammatory and immunomodulatory effects.

However, contradictory results have been described when they are applied to oligodendrocytes (OLGs), the cell type predominantly affected in MS. In this study we focus on the in vitro effect of statins on process outgrowth in OLN-93 cells, a well-characterized OLG-derived cell line, and ...
Read more : Statins have detrimental effects on remyelination in MS | Views : 2047 | Replies : 0


Doc says "...take statin, fish oil, and niacin for hear

My general physician has me on 80mg of statin, Carlson's fish oil, and a 1000mg of niacin. According to him, studies have shown that this combination has decrease the risk of a heart attack or stroke by 90 percent.

I always been on a high dose of statin since I found out that I have MS. I added the fish oil and niacin almost 3 months ago. What has been interesting is that I think ...
Read more : Doc says "...take statin, fish oil, and niacin for hear | Views : 2472 | Replies : 2




question

I am going for a Stem cell transplant next week. I have been on Lipitor for at least 4 years, to decrease the inflammation in my brain (and decrease my CRP) My question is , should I stop it so that the stem cells recognize where there is inflammation and damage?
Read more : question | Views : 2364 | Replies : 0




Statins prevent re-myelination?

Not trying to scare anyone off statins:

http://www.ncbi.nlm.nih.gov/pubmed/19349355

Curious what others think.
Read more : Statins prevent re-myelination? | Views : 3005 | Replies : 1






Interferon and atorvastatin may increase disease activity

The combination of 40 or 80 mg atorvastatin with thrice weekly, 44 mcg interferon beta-1a in persons with multiple sclerosis resulted in increased MRI and clinical disease activity. Caution is suggested in administering this combination.


http://tinyurl.com/5g4hao
Read more : Interferon and atorvastatin may increase disease activity | Views : 2622 | Replies : 0


 

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