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Discuss Tecfidera (BG-12, dimethyl fumarate) as an oral treatment for multiple sclerosis.

first PML case on tecfidera

Caveat emptor

http://www.reuters.com/article/2014/10/ ... 9720141022

article copied below:

(Reuters) - Biogen Idec Inc said on Wednesday sales of its big-selling new multiple sclerosis drug Tecfidera fell short of Wall Street's lofty expectations, and the company confirmed a serious brain infection in a patient who took the oral medication, sending its shares 7 percent lower.

Biogen reported the first case of progressive multifocal leukoencephalopathy (PML) in a Tecfidera patient, who ...
Read more : first PML case on tecfidera | Views : 7 | Replies : 0


Elevated Liver Numbers!

I've been on Tec for 4 weeks, 3 weeks at the standard dose and I've had a few mishaps with my labs. Initially, when I got labs to start the medication I had a borderline ANC of 1.8 which was concerning since Tec drops WBC counts. My neuro is being especially cautious and has ordered labs at 1,3, and 6 months so I just went in for my one month draw yesterday. The good news ...
Read more : Elevated Liver Numbers! | Views : 405 | Replies : 1


dry mouth?

I have been on this med for 4 months and the flushing only comes once in a while. But I have had extreme dry mouth ever since I started the medication. It usually starts within 3-4 hours of taking my first dose of the day. Does anyone else have this? If so what can I do to get rid of it?
Read more : dry mouth? | Views : 285 | Replies : 2


NICE recommends new treatment option for MS

NICE recommends new treatment option for multiple sclerosis Tecfidera (Dimethyl fumarate)

In final guidance, the National Institute for Health and Care Excellence (NICE) has recommended the use of Biogen Idec’s multiple sclerosis drug, dimethyl fumarate (also called Tecfidera).

The NHS now has a legal obligation to begin funding this treatment for eligible patients within the next 3 months...... Read More - http://www.ms-uk.org/tecfidera
Read more : NICE recommends new treatment option for MS | Views : 296 | Replies : 0


itching

My post was here but now it's gone. Can anyone tell me if aspirin will help with the intense itching from Tec? the flushing, or rather skin crawling with fire followed by pins and needles-ish itching kept me up all night and I ended up calling in sick today because I was so wiped out. Obviously, this is not a sustainable solution for dealing with side effects.


Can others please tell me what they do ...
Read more : itching | Views : 252 | Replies : 0


Tecfidera, my blog

Hi there,

I'm new here. Diagnosed with MS, about 6 months ago and started Tecfidera about two weeks ago.

I started a blog, initially meant to track my progress with Tecfidera. Basically, have a testimony of the good or the bad whichever comes as forums, naturally, show more bad than good. Which is normal because you tend to go there when things don't go great.

I'll try to keep it updated and cover more about ...
Read more : Tecfidera, my blog | Views : 326 | Replies : 0


Tecfidera - Light Headedness?

Hi All,
I am new to posting on the board but have been a long time reader. Everyone who adds to the dialogue are truly wonderful people for sharing and sharing some more of their personal stories.
My question: I have been on Tecfidera for roughly 9 weeks (2 months; 1 week). For the passed month I have been experiencing terrible light headedness. Not as much dizzy, no vertigo, just as if my blood sugar ...
Read more : Tecfidera - Light Headedness? | Views : 311 | Replies : 2


Tecfidera side effect: hair loss?

I have been experiencing a major increase in the amount of hair that I naturally lose from washing hair/brushing hair. It started a few weeks ago but seems to be gradually getting worse. My thyroid levels are good and haven't had any crazy changes...so I'm assuming this is a side effect of Tecfidera. I haven't seen a lot of other people experiencing the same thing on this particular medication though. Luckily I had really thick ...
Read more : Tecfidera side effect: hair loss? | Views : 554 | Replies : 4


Weight gain & numbness

Has anyone else gained weight? I've been on it for almost a month and gained 3lbs while eating less. And changing my diet. I've eliminated, gluten, sugar and all processed foods. I feel better, but I'm sure it's the diet. Also, last night for the very first time the top of my right foot and ankle went numb for a while. And it didn't 'tingle' after as if it had been 'asleep'. As it would ...
Read more : Weight gain & numbness | Views : 480 | Replies : 0


Do you have the ringing in your ears?

Feeling optimistic but man the ringing in your ears can make it hard to sleep at night. Anyone know of some vitamins that may help? :geek:
Read more : Do you have the ringing in your ears? | Views : 423 | Replies : 2


 

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