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Discuss Tecfidera (BG-12, dimethyl fumarate) as an oral treatment for multiple sclerosis.

Rash on hands and arms?

Hi, everyone. I was diagnosed on February 28, although my new neurologist who diagnosed me believes that I started showing symptoms eight years ago.

I started Tecfidera on March 11. I had a lot of stomach issues, and I still have some, but at least I can walk without being doubled over in pain. I followed Ladymac's recommendations and they definitely helped. Today, for the very first time, my face and neck turned red as ...
Read more : Rash on hands and arms? | Views : 583 | Replies : 2

Tecfidera & Men's Fertility

Hi, I'm hoping to get some information from people who may know information or be in a similar position. My husband has been diagnosed with MS and is due to start Tecfidera soon. We want to try for another baby but we are worried as we don't know if the drug can cause infertility or birth defects. We have asked the MS nurse assigned to him but she can't give us a real answer on ...
Read more : Tecfidera & Men's Fertility | Views : 928 | Replies : 0

Stabbing pain

I've been taking Tecfidera for about 4 months now, and for the most part I've left the gastro side effects behind.

Last night I took my pill late, just before bed. Every time I take it I have to eat something after or else the pill just sits high up in my esophagus. I find the capsules are very light, they almost seem cheaply made.

Anyway, I didn't eat anything last night and just went ...
Read more : Stabbing pain | Views : 1218 | Replies : 1

Do fumarates change into fumaric acid in vivo?

Need brainier folks than I for this one...

Dimethyl fumarate and clemastine fumarate are both alleged to have potential beneficial effects on some pwms for different reasons or unknown reasons. Dimethyl might reduce relapses. Clemastine might contribute to remyelination.

IF fumarates are changed into fumaric acids by our bodies, might it be fumaric acids that are helping?

Fumaric acid is produced in our skin when it is exposed to sunlight. Maybe vitamin d is just ...
Read more : Do fumarates change into fumaric acid in vivo? | Views : 2011 | Replies : 20

Ibuprofen instead of aspirin for flushing

Hi, I was wondering if anyone has tried ibuprofen instead of aspirin to help ward off flushing. I've been taking ibuprofen for years for arthritis and general body pain, and wondered if this could be taking instead of aspirin.
I asked my doctor and also researched ibuprofen for the flushing side effect from Tecfidera, and only came across taking aspirin for this.

I started taking Tecfidera on Sunday. On day one, I took one 325mg ...
Read more : Ibuprofen instead of aspirin for flushing | Views : 1716 | Replies : 0

What was your first day like on Tecfidera?

Hi, this is my first day on Tecfidera. I was just wondering how others did on their first day on Tec. This might help others who have concerns or worries about what to expect.

My experience so far... after 30 minutes, my face started feeling very warm. Like, if the sun was on your face on a hot summer day. That feeling lasted for about 20-30 minutes, then went away. Now, 4 hours into my ...
Read more : What was your first day like on Tecfidera? | Views : 1467 | Replies : 0

Dimethyl fumarate achieves no evidence of disease activity..

Dimethyl fumarate achieves no evidence of disease activity in MS patients

Data analysis of two previous trials has shown that a higher number of patients with relapsing remitting multiple sclerosis (RRMS) achieved no evidence of disease activity (NEDA), over a two year period, with delayed-release dimethyl fumarate (DMF) compared to a placebo...Read more -
Read more : Dimethyl fumarate achieves no evidence of disease activity.. | Views : 1388 | Replies : 1

Fever and wheezing on Tec **Update**

I'm on day 3 of taking three 120mg per day (two in the am, one in the pm).

I'm titrating very slowly because it's killing my stomach.

Anyway about 2 hours after the morning dose I started wheezing, bad enough that I can't lie down. I also have a dry cough.

I thought it could be reflux so I took some Gaviscon, which helped the tummy but not the breathing.

Now I have a headache, ...
Read more : Fever and wheezing on Tec **Update** | Views : 1577 | Replies : 6

Bariatric surgery and Tecfidera

I am about to start Tecfidera, and I am currently on a waiting list for bariatric surgery (Roux en Y or possibly gastric sleeve).

This is a long shot, but has anyone else gone through this procedure while taking Tecfidera?

I feel like I'm walking into catastrophe. My neurologist is very uninformed about the surgery, which is fine except that he's quite nonchalant and not inclined to do any research to help me - yet ...
Read more : Bariatric surgery and Tecfidera | Views : 1557 | Replies : 3

Always read the label – MS drug Tecfidera...

Always read the label – MS drug Tecfidera sites possible liver damage

Drug company Biogen has updated the possible side effects of MS drug Tecfidera, warning it may cause ‘significant liver injury’, which could require hospitalisation...Read more -
Read more : Always read the label – MS drug Tecfidera... | Views : 1454 | Replies : 1


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