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Discuss Tecfidera (BG-12, dimethyl fumarate) as an oral treatment for multiple sclerosis.

Tecfidera ‘could be increasing B-cells’

Recent studies have shown that Tecfidera decreased certain immune cells, of both B-, and T-cell type in MS patients. Studies have also indicated that this class of drugs affects the signalling through IL-10, a key regulator of immune responses. This anti-inflammatory cytokine is most often released by regulatory B-, and T-cells (Bregs/Tregs)...Read more -
Read more : Tecfidera ‘could be increasing B-cells’ | Views : 1099 | Replies : 0

Flushing and makeup

3 months in on Tec and the flushing is still daily. If the 6 month check-up MRI shows nothing new, I can survive getting a bit red from time to time.

The problem is that the heat of the flushings are ruening my makeup, the foundation(ID bare minerals powder) kindoff separates from the skinn and gathers in spots on the face. I am not very vain but I would like to be able to wear ...
Read more : Flushing and makeup | Views : 1216 | Replies : 2

Choosing Meds - Insurance Issues?

Hey! I was recently diagnosed with RRMS and given three different beginning drug choices. Tecfidera, Gilenya, and Copaxone. I was told that my insurance (Fidelis Medicaid) would fully cover the Copaxone, but that they don't currently cover either Gilenya or Tecfidera. However, the neuro resident I met with concerning the med information was very confident that although they would decline covering the medication a first time, so long as they re-submitted it a second time ...
Read more : Choosing Meds - Insurance Issues? | Views : 1401 | Replies : 4

One month on Tec

I have now been using tecfidera for one month. This is my first drug against MS, actually my first drug ever not counting the occasional antibiotic.
1 week on the low dose and three on full dose, these are my experiences.

First week on tec I got some flushing. It varied from mild blush to full-scale tomato woman. The flushing lasted about an hour every time. I had a mild nausea, nothing that I ...
Read more : One month on Tec | Views : 1319 | Replies : 1

Tecfidera & Constipation?

I have been on Tecfidera for a little over 2 years now. For the first 6 months or so I had stomach pains and nausea with occasional vomiting. All that has pretty much disappeared. I also had the flushing, which I still get, but for a short amount of time. It's tolerable. Since I started taking Tecfidera though, I have been have problems with constipation. This seems to be not the norm, since many are ...
Read more : Tecfidera & Constipation? | Views : 1529 | Replies : 4

DMF ‘reduces disease activity long-term in MS’

Delayed-release dimethyl fumarate (DMF, also known as gastro-resistant DMF) is effective at lowering disease activity long-term in patients with relapsing-remitting multiple sclerosis (RRMS), according to Eva Havrdova, MD, of Charles University of Prague... Read More -
Read more : DMF ‘reduces disease activity long-term in MS’ | Views : 1351 | Replies : 0

Have Your doctor test lymphocyte count

I was bummed of course when I got the news of MS, but going on a safe oral was good news for me. I was immediately put on Tecfidera and had little to no side effects. I did everything to prepare for the worst side effects, but after two weeks it was smooth sailing. However, a year into it I started having skin issues and I lost a ton of my pigmentation due to vitiligo. ...
Read more : Have Your doctor test lymphocyte count | Views : 1917 | Replies : 3

Tecfidera Recurrent Side-effects (after initial side-effects

I have been on Tecfidera for a little over 2 years. I had the typical GI side-effects for 2 months when I first started the drug, but for the most part (except for 5 days of nausea 6 months into it) it has been smooth rolling until recently. Recently I had three weeks with nausea and a bloated and hard upper stomach. That went away but now I have been having diarrhea for one week. ...
Read more : Tecfidera Recurrent Side-effects (after initial side-effects | Views : 4918 | Replies : 16

New to Tecfidera

Hi everyone,

I am new to the board and I got diagnosed woth MS last year. I will be starting Tecfidera after having a bad experience with Copsxone. Is there any side effects that I should expect?
Read more : New to Tecfidera | Views : 1954 | Replies : 5

How similar are Tecfidera and Fumaderm?

I am asking because I have plans to do extensive traveling abroad and I am scratching my head as to how I might continue to take DMD's while I am gone. I would have to maintain an insurance policy stateside while I am gone to have it covered by insurance and that simply isn't possible. I do plan to have travel insurance but they do not cover pre-existing conditions. I was thinking if Tec and ...
Read more : How similar are Tecfidera and Fumaderm? | Views : 1768 | Replies : 2


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