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News News of Tecfidera (BG-12, dimethyl fumarate)

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Discuss Tecfidera (BG-12, dimethyl fumarate) as an oral treatment for multiple sclerosis.

MS drug Tecfidera's gastrointestinal side-effects......

MS drug Tecfidera's gastrointestinal side-effects influence ongoing use

Large proportions of patients starting on dimethyl fumarate (Tecfidera) for multiple sclerosis appear to need additional medications to manage the drug's gastrointestinal and other adverse effects, and a substantial minority are ultimately unable to tolerate the drug, multiple studies reported here found.

These findings were confirmed in the manufacturer's own studies -- for example, more than half of patients in an open-label study took over-the-counter medications to ...
Read more : MS drug Tecfidera's gastrointestinal side-effects...... | Views : 789 | Replies : 0


New data reinforce efficacy of Tecfidera®

New data reinforce efficacy of Tecfidera® in MS patients with high disease activity

New data reinforce the efficacy of Tecfidera in a wide range of patients with relapsing-remitting multiple sclerosis (RRMS), as well as support its favorable safety and tolerability profile in the real-world setting. These data were presented by Biogen Idec at the 66th American Academy of Neurology (AAN) annual meeting in Philadelphia...... Read More - http://www.ms-uk.org/BG12
Read more : New data reinforce efficacy of Tecfidera® | Views : 776 | Replies : 0


Tecfidera approved by Scottish Medicines Consortium

A new oral drug for people with relapsing-remitting multiple sclerosis is to be made available in Scotland.

Tecfidera (dimethyl fumarate) a first-line oral treatment could be an alternative to injectable medication for people with the most common form of multiple sclerosis (RRMS).... Read More - http://www.ms-uk.org/BG12
Read more : Tecfidera approved by Scottish Medicines Consortium | Views : 536 | Replies : 0


Alcohol and Tecfidera

Dear all,

I got a question about tecfidera. I'm from germany and Tecfidera was approved in Germany few months ago. My doctor told me that the americans use it since few years.
I can't find answears in german forums because there is not enough experience.

My question is: Is it possible to drink some beer after work and few hours later i can take tecfidera ? Or is that inadvisable ? My doctor says its ...
Read more : Alcohol and Tecfidera | Views : 1701 | Replies : 5


NICE initial thumbs down for oral MS drug Tecfidera

NICE Appraisal Committee has stated it cannot recommend oral MS drug Tecfidera.

Appraisal Committee's preliminary recommendations Tecfidera (dimethyl fumarate) for treating adults with relapsing–remitting multiple sclerosis.

- The Committee is minded not to recommend dimethyl fumarate within its marketing authorisation, that is, for treating adults with relapsing–remitting multiple sclerosis........ Read More - http://www.ms-uk.org/BG12
Read more : NICE initial thumbs down for oral MS drug Tecfidera | Views : 802 | Replies : 0


Round 2 worse than the 1st

Been on and off tecfidera for 1 month now and it hasn't gotten any easier. First round, got to week 3 no problems then BOOM, curled up in the fetal position with stomach pain. Stopped taking the meds for 4 days then had an allergic reaction to something (?)- hives covered everything from my scalp to my toes (no known allergies prior)…Was on steroids and benedryl and feel like I got that under control and ...
Read more : Round 2 worse than the 1st | Views : 675 | Replies : 0


Tecfidera® approved in the European Union

Tecfidera® (dimethyl fumarate) has been approved by the European Commission (EC) as a first-line oral treatment for people with relapsing-remitting multiple sclerosis (RRMS), the most common form of multiple sclerosis (MS). Biogen Idec will begin to introduce Tecfidera in initial European Union (EU) countries in the coming weeks..... Read More - http://www.ms-uk.org/BG12
Read more : Tecfidera® approved in the European Union | Views : 547 | Replies : 0


Tecfidera and glutathione

So, I have been reading about how Tecfidera works by depleting levels of glutathione in your body. In my research I can't find info about whether I should, when I start Tecfidera next week, stop using the glutathione supplement I take? What about other supplements that are supposed to raise levels of glutathione, like milk thistle? If Tecfidera works by depleting glutathione, seems counter-productive to take supplements that increase glutathione. Thoughts?
Read more : Tecfidera and glutathione | Views : 1082 | Replies : 4


BG-12 and IC

I began taking Tecfifera on Sat and noticed my IC is really painful. Wondering if its related to starting this new med.

Anyone else have this issue? My bladder really hurts ;@(
Read more : BG-12 and IC | Views : 594 | Replies : 0


Tecfidera - cold and flu - Anyone getting sick more?

I was on Tysabri for several years. In September I moved to Tecfidera. I think I have been on it for 3.5 months or so. The stomach issues stopped after the first few weeks, but the flushing happens every time like clockwork. I have gotten used to that as well as much as I can.

My question is, has anyone gotten sick more frequently while on Tecfidera? I have had a cold that just won't ...
Read more : Tecfidera - cold and flu - Anyone getting sick more? | Views : 1712 | Replies : 9


 

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