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Discuss Tecfidera (BG-12, dimethyl fumarate) as an oral treatment for multiple sclerosis.

Tecfidera - cold and flu - Anyone getting sick more?

I was on Tysabri for several years. In September I moved to Tecfidera. I think I have been on it for 3.5 months or so. The stomach issues stopped after the first few weeks, but the flushing happens every time like clockwork. I have gotten used to that as well as much as I can.

My question is, has anyone gotten sick more frequently while on Tecfidera? I have had a cold that just won't ...
Read more : Tecfidera - cold and flu - Anyone getting sick more? | Views : 1233 | Replies : 8


Pterostilbene as an Nrf2 activator

There has been much discussion regarding dimethyl fumarate's role as an Nrf2 activator. The following journal article reports that pterostilbene, which is an extract from blueberries, also activates Nrf2.

Reporter protein complementation imaging assay to screen and study Nrf2 activators in cells and living animals.
Anal Chem. 2013 Aug 6;85(15):7542-9.

    NF-E2-related factor-2 (Nrf2) activators promote cellular defense mechanism and facilitate disease prevention associated with oxidative stress. In the present study, Nrf2 activators were identified using ...
Read more : Pterostilbene as an Nrf2 activator | Views : 877 | Replies : 2


Good news for Tecfidera in Europe

European Medicines Agency determines that dimethyl fumarate in MS drug Tecfidera qualifies as a new active substance

Biogen Idec Inc. said the European Medicines Agency's Committee for Medicinal Products for Human Use determined that dimethyl fumarate in its drug Tecfidera qualifies as a new active substance...... Read More - http://www.ms-uk.org/BG12
Read more : Good news for Tecfidera in Europe | Views : 717 | Replies : 0


Stopping Tecfidera to get pregnant

Hey all!

I am new to this forum, but have had MS since 2007. I started Tecfidera about 5 months ago, switching from Avonex. I have a call into my neuro at the moment (since Tuesday anyway) to talk to him about stopping my treatment to get pregnant one more time. What I am curious about is whether or not anyone has any idea on how long you need to be off of Tecfidera before ...
Read more : Stopping Tecfidera to get pregnant | Views : 1336 | Replies : 5


First MRI

Hi. I am happy to report that I have a stable MRI. I started on Tecfidera in May. I was so relieved that this is working for me because I did not want to go back on Avonex! Good luck to all you Tec newbies out there.
Read more : First MRI | Views : 750 | Replies : 2


HELP!!! First day on Tecfidera. EEEEEEK!!!!!!!!!

OMG this stuff is diabolical! I had my first dose this morning of the 120mg capsule and made sure I ate a high protein breakfast of bacon, sausage, fried egg and toast before taking it. I can't take Aspirin though due to another medical condition. Thanks for the diet tips ;)

The nausea kicked in about an hour after taking it but wasn't too bad, just a ...
Read more : HELP!!! First day on Tecfidera. EEEEEEK!!!!!!!!! | Views : 1337 | Replies : 4


Tecfidera first 17 days and counting

my MS TECFIDERA experience http://tecfiderateresa.blogspot.com/

Just in case anything helps anyone considering it. I'm not in excruciating pain but I'm definitely not comfortable. Lol.

I'm having greater difficulties daily...but I'm trying to cope and get through it. Not the crying pain but more burping and twisted tummy grinds than I care to talk about. Hope the blog helps people trying too decide. I definitely feel there are more people's ...
Read more : Tecfidera first 17 days and counting | Views : 804 | Replies : 1


anyone have a fllareup since being on tecfidera

tecfidera flareup or not???
Read more : anyone have a fllareup since being on tecfidera | Views : 1959 | Replies : 5


Tecfidera and Psoriasis

I was on Tysabri for 6 years. I stopped and started Tecfidera. I was on Tec for 4 months and then I had two low white blood cell counts.
The week of the last WBC lab the skin on my hands and feet started peeling. My neuro had me stop taking carbamazepine and Tec. That was over a month ago. Last week after a skin biopsy it was diagnosed as Psoriasis. In Germany they treat ...
Read more : Tecfidera and Psoriasis | Views : 1334 | Replies : 7


4 year Tecfidera clinical efficacy and safety data

4 year Tecfidera clinical efficacy and safety data in patients with MS released

Latest results from the clinical trial program with BG-12 (dimethyl fumarate; Tecfidera, Biogen Idec) suggest sustained clinical efficacy and safety in patients with multiple sclerosis (MS) taking the drug for up to 4 years.

In addition, a separate post hoc analysis of the phase 3 pivotal Determination of the Efficacy and Safety of Oral Fumarate in Relapsing–Remitting MS (DEFINE) and Comparator and ...
Read more : 4 year Tecfidera clinical efficacy and safety data | Views : 1049 | Replies : 0


 

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