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Discuss Tecfidera (BG-12, dimethyl fumarate) as an oral treatment for multiple sclerosis.

Side effects

Hi all! Started Tecfidera about 10 days ago and wanted to know what side effects everyone is dealing with. I had the heat/bad flushing for a day or two. My main concern is the nausea and stomach pain. My MS dr actually had me cut back to one pill a day to alleviate some of this. Anyone else experience nausea/stomach pain? So hard not to be able to find more info on side effects because ...
Read more : Side effects | Views : 37003 | Replies : 167

Anyone taking this medication yet?


I have quite a bit of pressure from my doctor to take Tecfidera. I was told about all the "mild side effects". From what I have read about the side effects I am not sure that I would still be able to function at work or anywhere else for that matter. Has anyone started taking this medication and if so how tolerable are the side effects?

Read more : Anyone taking this medication yet? | Views : 3116 | Replies : 14

Oral treatment for MS, Tecfidera, approved for use in Canada

A new oral treatment for those living with multiple sclerosis has been approved for use in Canada.

Tecfidera is an oral medication recently approved by Health Canada..... Read More -
Read more : Oral treatment for MS, Tecfidera, approved for use in Canada | Views : 854 | Replies : 2

Ingredient in new MS drug, Tecfidera, linked to PML

The active ingredient in a drug that’s expected to become a popular treatment for multiple sclerosis has been linked to four European cases of a rare but sometimes fatal brain disease called progressive multifocal leukoencephalopathy (PML)........ Read More -
Read more : Ingredient in new MS drug, Tecfidera, linked to PML | Views : 1963 | Replies : 4

Cost Dimethyl fumarate (Techfiodra).

$ :confused: :confused: 50K a year! ... _price.php. I plan to go on it anyway. The $10 program they will start sounds good. This site says you can get a 3 year supply for $104 of cheaper with out docs script. Techfedora has been around for a long time. Just curious. ...
Read more : Cost Dimethyl fumarate (Techfiodra). | Views : 2132 | Replies : 6

Tecfidera efficacy & potential toxicity

I just finished reading the prescribing information for Tecfidera. Of the two studies cited, one did not show a significant effect on disease progression.

Biogen wrote:Tecfidera had a statistically significant effect on all of the relapse and MRI endpoints described above. There was no statistically significant effect on disability progression. The Tecfidera 240 mg three times daily dose resulted in no additional benefit over the Tecfidera 240 mg twice daily dose.

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Tecfidera - a mistake to make it oral?

Wow, maybe the newly released oral MS med Tecfidera (previously BG-12) should have been an injection med instead!! :-D Am anxious to hear how debilitating the nausea, vomiting & diarrhea side effects are. Apparently they're enough for patients to stop the med.

Although an irritable digestive system might be characterized as "minor" and not very life-threatening, dealing with constant and/or severe stomach flu-type symptoms could easily ...
Read more : Tecfidera - a mistake to make it oral? | Views : 6573 | Replies : 24

FDA approves new oral multiple sclerosis drug, Tecfidera

The Food and Drug Administration said Wednesday it approved a new drug from Biogen Idec to control multiple sclerosis in adults with hard-to-treat forms of the disease.

The twice-a-day capsules, called Tecfidera, offer a new option for multiple sclerosis, a debilitating disease in which the body attacks its own nervous system. Cambridge, Mass.-based Biogen Idec already sells two other drugs for the disease, but both require injections.......Read More -
Read more : FDA approves new oral multiple sclerosis drug, Tecfidera | Views : 1372 | Replies : 0

New to ThisIsMS BG12 User

I am a 54 year old female with RRMS. I was dx'd in 2000 but had MS for about 6 years before that. I didn't use any meds until the BG12 trial which I started in January of 2008 for me so I have been on the correct dose since the start. It was measured against a higher dose, placebo and copaxone.

Since it received FDA approval today, I can now gladly answer any questions ...
Read more : New to ThisIsMS BG12 User | Views : 2708 | Replies : 22


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