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News News of Tecfidera (BG-12, dimethyl fumarate)

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Discuss Tecfidera (BG-12, dimethyl fumarate) as an oral treatment for multiple sclerosis.

My Experieince with Tecfidera

I am new to this board so I would like to start out by saying I have never been able to take maintenance drug for MS because of the sever reaction that my body has to the drugs. I watched Tecfidera through the FDA and watch in amazement when the only major side effect reported were flushing and food poisoning. I was so excited that there was finally a drug that I could take.

I ...
Read more : My Experieince with Tecfidera | Views : 6983 | Replies : 21


Significant quality-of-life benefit with BG-12

A post hoc analysis of phase 3 studies in patients with relapsing-remitting multiple sclerosis (RRMS) clearly showed that those taking the oral agent BG-12 (dimethyl fumarate; Tecfidera, Biogen Idec Inc.) experienced significant improvements in physical and mental functioning, general well-being, and overall health status, whereas those receiving placebo typically reported declines in these measures of quality of life....... Read More - http://www.ms-uk.org/index.cfm/BG12
Read more : Significant quality-of-life benefit with BG-12 | Views : 874 | Replies : 1


Side effects

Hi all! Started Tecfidera about 10 days ago and wanted to know what side effects everyone is dealing with. I had the heat/bad flushing for a day or two. My main concern is the nausea and stomach pain. My MS dr actually had me cut back to one pill a day to alleviate some of this. Anyone else experience nausea/stomach pain? So hard not to be able to find more info on side effects because ...
Read more : Side effects | Views : 43090 | Replies : 175


Anyone taking this medication yet?

Hello,

I have quite a bit of pressure from my doctor to take Tecfidera. I was told about all the "mild side effects". From what I have read about the side effects I am not sure that I would still be able to function at work or anywhere else for that matter. Has anyone started taking this medication and if so how tolerable are the side effects?

Alicia
Read more : Anyone taking this medication yet? | Views : 3480 | Replies : 14


Oral treatment for MS, Tecfidera, approved for use in Canada

A new oral treatment for those living with multiple sclerosis has been approved for use in Canada.

Tecfidera is an oral medication recently approved by Health Canada..... Read More - http://www.ms-uk.org/index.cfm/BG12
Read more : Oral treatment for MS, Tecfidera, approved for use in Canada | Views : 927 | Replies : 2


Ingredient in new MS drug, Tecfidera, linked to PML

The active ingredient in a drug that’s expected to become a popular treatment for multiple sclerosis has been linked to four European cases of a rare but sometimes fatal brain disease called progressive multifocal leukoencephalopathy (PML)........ Read More - http://www.ms-uk.org/index.cfm/BG12
Read more : Ingredient in new MS drug, Tecfidera, linked to PML | Views : 2097 | Replies : 4


Cost Dimethyl fumarate (Techfiodra).

$ :confused: :confused: 50K a year! http://pipeline.corante.com/archives/20 ... _price.php. I plan to go on it anyway. The $10 program they will start sounds good. This site says you can get a 3 year supply for $104 of cheaper with out docs script. Techfedora has been around for a long time. Just curious. ...
Read more : Cost Dimethyl fumarate (Techfiodra). | Views : 2290 | Replies : 6


Tecfidera efficacy & potential toxicity

I just finished reading the prescribing information for Tecfidera. Of the two studies cited, one did not show a significant effect on disease progression.

Biogen wrote:Tecfidera had a statistically significant effect on all of the relapse and MRI endpoints described above. There was no statistically significant effect on disability progression. The Tecfidera 240 mg three times daily dose resulted in no additional benefit over the Tecfidera 240 mg twice daily dose.

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Read more : Tecfidera efficacy & potential toxicity | Views : 3556 | Replies : 7


Tecfidera - a mistake to make it oral?

Wow, maybe the newly released oral MS med Tecfidera (previously BG-12) should have been an injection med instead!! :-D Am anxious to hear how debilitating the nausea, vomiting & diarrhea side effects are. Apparently they're enough for patients to stop the med.

Although an irritable digestive system might be characterized as "minor" and not very life-threatening, dealing with constant and/or severe stomach flu-type symptoms could easily ...
Read more : Tecfidera - a mistake to make it oral? | Views : 7488 | Replies : 24


FDA approves new oral multiple sclerosis drug, Tecfidera

The Food and Drug Administration said Wednesday it approved a new drug from Biogen Idec to control multiple sclerosis in adults with hard-to-treat forms of the disease.

The twice-a-day capsules, called Tecfidera, offer a new option for multiple sclerosis, a debilitating disease in which the body attacks its own nervous system. Cambridge, Mass.-based Biogen Idec already sells two other drugs for the disease, but both require injections.......Read More - http://www.ms-uk.org/index.cfm/BG12
Read more : FDA approves new oral multiple sclerosis drug, Tecfidera | Views : 1418 | Replies : 0


 

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