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News News of Tysabri (Antegren or Natalizumab)

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A board to discuss the newly-released drug Tysabri, (formerly known as Antegren) as a treatment for Multiple Sclerosis

Tysabri ‘no help in secondary progressive MS’

Tysabri didn't slow disability progression in patients with secondary progressive multiple sclerosis (SPMS).
...Read more - http://www.ms-uk.org/MSnews
Read more : Tysabri ‘no help in secondary progressive MS’ | Views : 85 | Replies : 0


Imaging biomarker diagnoses PML in Tysabri patients

A group of T2 weighted hyperintensities that disseminate in what is called a “punctate pattern” (PP) may directly precede the appearance of progressive multifocal leukoencephalopathy (PML) lesions, according to a new study published in Neurology...Read more - http://www.ms-uk.org/MSnews
Read more : Imaging biomarker diagnoses PML in Tysabri patients | Views : 289 | Replies : 0


Tysabri ‘more effective’ than Gilenya, study claims

A retrospective analysis has found Tysabri is more effective than Gilenya in preventing relapses in patients with relapsing-remitting multiple sclerosis (RRMS)...Read more - http://www.ms-uk.org/MSnews
Read more : Tysabri ‘more effective’ than Gilenya, study claims | Views : 466 | Replies : 0


MS drug linked to rising JC virus antibody levels

People who take the drug Tysabri for multiple sclerosis may have up to a 10 times greater risk of developing a risk biomarker for activity of a virus that can lead to an often fatal brain disease, according to a study published in online issue of Neurology Neuroimmunology and Neuroinflammation..Read more - http://www.ms-uk.org/MSnews
Read more : MS drug linked to rising JC virus antibody levels | Views : 478 | Replies : 0


PML case reported despite negative JCV test

A case of progressive multifocal leukoencephalopathy (PML) associated with Tysabri has been reported in an MS patient who had tested negative for the JC virus (JCV) antibodies just two weeks before symptoms developed...Read more - http://www.ms-uk.org/MSnews
Read more : PML case reported despite negative JCV test | Views : 555 | Replies : 0


Considering Tysabri - questions...

Hello,

I won't repeat a lot of my story, which you can read in all of its turn-of-the-screw (updated! new!) glory here: introductions-f20/topic27058.html

I got some labs back today. I am JCV negative, which is a relief since I'm consideing Tysabri. I haven't seen the actual result to see where I am on the scale yet, but apparently it's below the marker.

I have some questions and would appreciate ...
Read more : Considering Tysabri - questions... | Views : 1174 | Replies : 13


New to all of this - with lots of questions!

Hello my name is Lindsey. I am so glad to have found this site and an ability to connect with other MS patients!! I have never known one person with it and feel like none of my family or friends really understand what I'm going through. I've gotten to the point where when they ask how I'm feeling I just say "Ok" because I don't have the energy to explain all my mysterious ailments. They ...
Read more : New to all of this - with lots of questions! | Views : 561 | Replies : 5


Studies investigate possible PML vaccine

The JC polyomavirus is reported to be a persistent but otherwise asymptomatic kidney infection in a large portion of healthy people. However, in those with hereditary or acquired immune deficiency, a mutated form of the JC polyomavirus may lead to progressive multifocal leukoencephalopathy (PML), a central nervous system (CNS) infection characterised by progressive inflammation of the white matter of the brain. This is of particular interest in the treatment of multiple sclerosis (MS) with Tysabri, ...
Read more : Studies investigate possible PML vaccine | Views : 534 | Replies : 0


No conclusions over best drug for Multiple Sclerosis

Two studies - one from France, the other from Denmark - came to conflicting conclusions about whether Tysabri or Gilenya offers better efficacy, researchers have reported here... Read More - http://www.ms-uk.org/MSnews
Read more : No conclusions over best drug for Multiple Sclerosis | Views : 1094 | Replies : 0


Pregnancy ‘not neuroprotective for women with MS who stop...

Pregnancy ‘not neuroprotective for women with MS who stop taking Tysabri’

The possible protective effect of pregnancy on multiple sclerosis activity in women does not extend to patients who stop taking Tysabri after conceiving, researchers revealed at the 31st congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS)... Read more - http://www.ms-uk.org/MSnews
Read more : Pregnancy ‘not neuroprotective for women with MS who stop... | Views : 650 | Replies : 0


 

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