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A board to discuss the newly-released drug Tysabri, (formerly known as Antegren) as a treatment for Multiple Sclerosis

Detecting PML early could lessen damage to MS patients...

Detecting PML early could lessen damage to MS patients using Tysabri

A recent study has found that early detection of Progressive Multifocal Leukoencephalopathy (PML) could decrease the damage to Multiple Sclerosis (MS) patients using Tysabri...Read more - http://www.ms-uk.org/detecting-pml-early-could-lessen-damage-ms-patients-using-tysabri-170117
Read more : Detecting PML early could lessen damage to MS patients... | Views : 997 | Replies : 0


Tysabri may be more effective than Gilenya...

Tysabri may be more effective than Gilenya at reducing disease activity in MS patients, study says

An indirect comparison of results from randomised clinical trials in relapsing-remitting multiple sclerosis patients suggests that Tysabri (natalizumab) is more effective than Gilenya (fingolimod) at reducing disease activity...Read more - http://www.ms-uk.org/tysabri-may-be-more-effective-gilenya-reducing-disease-activity-ms-patients-study-says-071016
Read more : Tysabri may be more effective than Gilenya... | Views : 1230 | Replies : 0




JC Virus ‘carries mutation that amplifies PML’

A mutation in a mouse model of the John Cunningham (JC) virus, which causes progressive multifocal leukoencephalopathy (PML), allows the virus to evade the host immune responses in people with multiple sclerosis (MS), according to a study into the mechanisms of PML...Read more - http://www.ms-uk.org/MSnews
Read more : JC Virus ‘carries mutation that amplifies PML’ | Views : 1073 | Replies : 0


vedolizumab (alternative to natalizumab)

Vedolizumab (Entyvio) is an anti-integrin α4β7 approved for inflammatory bowel disease. Could this be used in someone with a natalizumab allergy or in a resource-poor area? Perhaps this could be a reasonable treatment for someone with both multiple sclerosis and inflammatory bowel disease?

Just curious about anyone's thoughts.

-cent
Read more : vedolizumab (alternative to natalizumab) | Views : 697 | Replies : 0


Natalizumab as a first line of treatment any advice?

Hi All,

I had been recently diagnosed as a case of Multiple sclerosis with active inflammation and had my first attack a month ago. Intravenous steroids were given and am currently on Oral steroids for tapering dosage. I had paraesthesias and visual symptoms in right eye, but after steroid therapy, currently i dont have any symptoms except for Urgency and frequency of urination, no incontinence though. My Neurologist after reviewing my clinical profile and MRI ...
Read more : Natalizumab as a first line of treatment any advice? | Views : 1589 | Replies : 7


Tysabri ‘no help in secondary progressive MS’

Tysabri didn't slow disability progression in patients with secondary progressive multiple sclerosis (SPMS).
...Read more - http://www.ms-uk.org/MSnews
Read more : Tysabri ‘no help in secondary progressive MS’ | Views : 967 | Replies : 0


Imaging biomarker diagnoses PML in Tysabri patients

A group of T2 weighted hyperintensities that disseminate in what is called a “punctate pattern” (PP) may directly precede the appearance of progressive multifocal leukoencephalopathy (PML) lesions, according to a new study published in Neurology...Read more - http://www.ms-uk.org/MSnews
Read more : Imaging biomarker diagnoses PML in Tysabri patients | Views : 888 | Replies : 0


Tysabri ‘more effective’ than Gilenya, study claims

A retrospective analysis has found Tysabri is more effective than Gilenya in preventing relapses in patients with relapsing-remitting multiple sclerosis (RRMS)...Read more - http://www.ms-uk.org/MSnews
Read more : Tysabri ‘more effective’ than Gilenya, study claims | Views : 1046 | Replies : 0


MS drug linked to rising JC virus antibody levels

People who take the drug Tysabri for multiple sclerosis may have up to a 10 times greater risk of developing a risk biomarker for activity of a virus that can lead to an often fatal brain disease, according to a study published in online issue of Neurology Neuroimmunology and Neuroinflammation..Read more - http://www.ms-uk.org/MSnews
Read more : MS drug linked to rising JC virus antibody levels | Views : 1001 | Replies : 0


 

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