The virus seems like a major risk, maybe not worth it. My dad hates the idea as well after reading up on it.

The thing about it is the risk goes up the longer you are on it, then if you get off of it you are kind of screwed because you get worse than you were before and very quickly. Am I wrong about any of this?

Any experiences with RRMS?

Sadly, the number of PML cases has jumped to 298 an increase of 14 over the previous month. The total number of deaths associated with this are 63.

http://chefarztfrau.de/?page_id=716

I am trying to decide if I should start Tysabri. One of my biggest fears is the rebound effect of having to stop the Tysabri. I don't have any garantee I can take it. I guess 2 yrs max.
Bg-12 is soon to come out we hope. I know it is not suppose to be as good.
I am progressing and that scares me. I do think Ty is the best drug.
I have to ...

Kirsty has sent in her 18th & 19th Tysabri infusion updates.

You can read her new diary entries at http://bit.ly/u3SoFn

Jill has kindly sent in her last and final Tysabri diary entry, as she is switching to Gilenya due to JC Virus results.

We would like to thank Jill for all her Tysabri diaries and wish her good luck with Gilenya.

You can read Jill's final diary entry at ...

Biogen Idec and Elan Corporation announced a global Phase 3b study that is being conducted to evaluate the effectiveness of Tysabri as a treatment for secondary-progressive multiple sclerosis (SPMS).

The Ascend study is part of an ongoing commitment of both Biogen Idec and Elan to find ways to improve the well-being of patients with multiple sclerosis. Ascend (A Study to Characterize the Efficacy of Natalizumab on Disability in SPMS) is a double-blind, placebo-controlled study ...

Cytheris SA, a privately held clinical-stage biopharmaceutical company focused on treating lymphopenia driven diseases, announced that the European Commission has granted an orphan designation for Cytheris' CYT017, glycosylated recombinant human interleukin-7 (glycosylated r-h-IL7), for the treatment of Progressive Multifocal Leukoencephalopathy (PML).

Additionally, Cytheris obtained scientific advice for a phase IIb study protocol with CYT107 in HIV-related PML. Cytheris has reached an agreement with the EMA on the key study endpoints. Cytheris will start this ...

I am new to this forum and looking for answers regarding Tysabri.

I was dx'd w/ r/r MS 11 years ago. Once I got consistent on Rebif, I have not had any relapses in more then 5 years. (I used to average about 4/year.) I have little issues pop up here and there, but nothing too concerning. My biggest issue is fatigue. I get a yearly checkup from my doctor. My MRI's are always clear. ...

Natalizumab interruption results in a high rate of MRI and clinical MS disease activity recurrence



After a 24-week cessation of natalizumab treatment, a high rate of magnetic resonance imaging (MRI) and clinical disease activity recurs in patients with multiple sclerosis (MS) according to new research.

Natalizumab treatment duration has been associated with the development of progressive multifocal leukoencephalopathy (PML), a rare but often lethal and untreatable disorder of the central nervous system, characterized by ...

7th infusion of natalizumab or tysabri been diagnosed for 9 months now, was a real shock at the time, i lost all power to my arms and lower limbs, my sight and had severely chronic memory loss, was quite scary as a teenager been told i had MS my future was planned before that day i wanted to be a nurse and travel but when i was told i could be in a wheelchair for ...