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A board to discuss the newly-released drug Tysabri, (formerly known as Antegren) as a treatment for Multiple Sclerosis

Tysabri: Then and Now

It is amazing the changes in the way you go to your DR and asked to be put on Tysabri; Then and Now.
Then: Gary was an immediate canidate, perfect canidate for Tysabri. "As soon as it comes out, I'll put you on it"
Now: It won't do Gary any good. It doesn't do good for Progressive MS. You know you could die on it. It don't make you better. You know you could die ...
Read more : Tysabri: Then and Now | Views : 1983 | Replies : 1

Anyone gotten insuance remibursement yet?

I am going for my 2nd infusion tomorrow - which my neuro is requiring a $2500 payment for until insurance companies start paying. I don't know if anyone has gotten reimbursed yet for Tysabri - a med that is FDA approved! Another 2500 on the credit card, thanks oxford liberty.

I'm keeping my fingers crossed and will report back when I have more info. I haven’t had any major attacks since starting last month, so ...
Read more : Anyone gotten insuance remibursement yet? | Views : 5225 | Replies : 18

New data

HarryZ - this hasn't been a good week for you relating to Tysabri. If I had your address I'd sent you a bottle of Whisky - you could do with a stiff drink now that it is available in Canada :)
Read more : New data | Views : 2097 | Replies : 1

Tysabri now in Canada.

Health Canada Grants Approval of TYSABRI(TM) (natalizumab) for the Treatment of Multiple Sclerosis Following Priority Review

Wednesday October 4, 8:00 am ET
First New Class of Treatment in Ten Years Shown to Reduce Rate of Relapses by 68%(1)

MISSISSAUGA, Ontario & DUBLIN, Ireland--(BUSINESS WIRE)--Biogen Idec Canada and Elan Corporation, plc announced today that following a priority review process, Health Canada has granted approval to TYSABRI(TM) (natalizumab) for the treatment of relapsing-remitting multiple sclerosis (MS).(2) TYSABRI ...
Read more : Tysabri now in Canada. | Views : 2279 | Replies : 3

Tysabri research ... PR_143.htm

I would love to get my hands around the neck of the bastard who dreamt up this disease. As if physical disability wasn't bad enough they had to throw in cognitive problems!

Read more : Tysabri research | Views : 1909 | Replies : 0

Tysabri and Diabetes

Does anyone know if being a diabetic (either pill and diet modification or diet modification only) will hinder someone from getting Tysabri? I have a friend at a @#$%^&*()^% DR today and I know that DR will probably say you can't take it because of his blood sugar. He has been borderline diabetic for a couple of years and steroids has really pushed it over the edge.
Read more : Tysabri and Diabetes | Views : 2873 | Replies : 4

Biogen deal for PML

from the Boston Globe

Alnylam, Biogen to partner on brain disease treatment
Alnylam Pharmaceuticals Inc. of Cambridge said it will collaborate with Biogen Idec Inc. to develop a treatment for a rare brain disease found in three patients taking Biogen Idec's multiple sclerosis drug Tysabri. Alnylam said Biogen Idec, also of Cambridge, would fund research to find a treatment for the disease, progressive multifocal encephalopathy. Alnylam will receive $5 million upfront and could earn up ...
Read more : Biogen deal for PML | Views : 5684 | Replies : 24

TOUCH and the required MRI

Gary is in the VERY SLOW process of getting in the TOUCH program to receive Tysabri. He was required to have a MRI of the brain within the past 6 months. The Neuro nurse stated that the DR would look at the MRI and see if he was a canidate for Tysabri. Other than the obvious PML, what are they looking for?
Read more : TOUCH and the required MRI | Views : 5039 | Replies : 15

Natalizumab benefits

Natalizumab Has Benefits on Disability and Quality of Life in Patients With Relapsing MS: Presented at EFNS
By Chris Berrie

GLASGOW, UK -- September 11, 2006 -- Monotherapy with the alpha4 integrin antagonist natalizumab results in significant improvements in scores on health-related quality of life (QoL) questionnaires in patients with relapsing-remitting multiple sclerosis (MS), according to results of a substudy from a multicentre, randomised, double-blind, placebo-controlled, phase 3 clinical trial.

The findings were presented here ...
Read more : Natalizumab benefits | Views : 2710 | Replies : 2

2nd infusion redux

I hesitate to tell the list this until I know something more definite but 7 minutes into my 2nd Tysabri infusion on Wednesday I had an anti-phylactic (allergic) reaction. Turned bright red, couldn't breath and felt like the top of my head was going to explode. Also managed to lose my breakfast. The nurse turned off the Tysabri and gave me Benedril and 250 mg of solumedrol. Not fun but all I could think was ...
Read more : 2nd infusion redux | Views : 7091 | Replies : 23


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