I don't have any info on the two used together. The only drug I know for sure you can't combine with LDN is any narcotic, like pain relievers. But I wish I'd known about LDN before I did Novantorone! Some people handle the chemo OK, but the side effects were harsh for me, and I had to quit after 1 yr because it caused my LVEF heart function to go down 10 points. And impact to the heart can occur years later from this drug. So I was slowly recovering from the chemo since 5/03, then I started LDN 2/04 and I am zooming in recovery after just 1 month, about to reitre my cane!