Combination of Rebif® and mycophenolate mofetil (Cellcept®)

A board to discuss the Multiple Sclerosis modifying drug Rebif

Combination of Rebif® and mycophenolate mofetil (Cellcept®)

Postby Olgica » Sun Aug 07, 2005 9:09 am

Hi!I have got MS 12 years ago.I am on Rebif since 1996.I have took it year and half.I have stoped because Rebif was experimental drug that time and it doesn't approved in my country.Rebif was so much expensive.I am on Rebif again.I am taking it already 4 years.I feel great and noone could possible that I am MS-er.I have had atack this june first time since I am on Rebif,because of that my neuro prescribed me CellCept 250mg X 2 times on day.I don't have any problems with that combination,but I was wondering do any of You take Rebif and CellCept!?Tell me if You take it how do u feel?
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Re: Combination of Rebif and Cellcept

Postby batpere » Sun Aug 07, 2005 11:18 am

Olgica wrote:I am on Rebif since 1996. I have had atack this june first time since I am on Rebif, because of that my neuro prescribed me CellCept 250mg X 2 times on day. I don't have any problems with that combination,but I was wondering do any of You take Rebif and CellCept!? Tell me if You take it how do u feel?


I have been taking Avonex (same substance as Rebif, just injected in the muscle) for 7 years and the neuro added CellCept (1000mg twice a day) about a year ago because of continuing lesions. I am awaiting the results of a recent mri to see if the combination was more effective.

I don't like having to be more careful not to be around sick people because of my suppressed immune system. The physical side effects of the CellCept are very minor for me - just a slight sick-to-the-stomach feeling. I'll consider switching to Copaxone and LDN if this Avonex+CellCept still isn't enough.
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Postby jazzcat » Thu Aug 25, 2005 12:09 pm

Hi all,

I haven't heard of cell-cept. What is that? I am on Rebif and have been for about 2 years. I am about to have the first MRI since my diagnosis two years ago.

Please fill me in about cell-cept.

Thanks,
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Postby batpere » Thu Sep 29, 2005 3:28 am

jazzcat wrote:I haven't heard of cell-cept. What is that? I am on Rebif and have been for about 2 years. I am about to have the first MRI since my diagnosis two years ago.


It's an immune system suppressant that heart transplant patients take to
avoid organ transplant rejection. It comes with this warning:

WARNING: Increased susceptibility to infection and the possible development of lymphoma may result from immunosuppression. Only physicians experienced in immunosuppressive therapy and management of renal or cardiac transplant patients should use CellCept. Patients receiving the drug should be managed in facilities equipped and staffed with adequate laboratory and supportive medical resources. The physician responsible for maintenance therapy should have complete information requisite for the follow- up of the patient.

After some patients had problems, my neuro now requires blood tests
every 3 months before they will write the next rx. I'm growing
increasingly uneasy about continuing to take it. However, progression
has stopped since I added it to the Avonex I've been taking for 7 years.
Not an easy call.
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