nikki9962 wrote:I did start Rebif at the end of June this year and all I find it is doing is causing bruising and site pain.. my symptoms were gone completely from the IV steroids - not the REBIF
There are other options. Have you considered Avonex? The "flu like" side effects are about the same but there are minimal injection site reactions. On rare occasions I might get a small nickel sized bruise. This might occur about once every 4-5 months or so. The Ifn-B dosage with Avonex is lower than it is with Rebif but then there is also a greater absorbtion efficiency with an intramuscular injection (Avonex) as opposed to a subcutaneous injection (Rebif & Betaseron), i.e., roughly 80% and 40% respectively.
On another note, the key with therapy is to slow the progression of disability. A problem with MS is that there are ongoing subclinical attacks. These are attacks that can be seen on MRI but do not produce symptoms. It's believed that over time the subclinical attacks will cause enough damage such that they produce new symptoms. A while back there was a link posted to a presentation which discussed this very nicely. However, I can't find it right now in my bookmarks and the closest thing I can find in that subject area is this paper
Here's a bit of history on my own situation. I had my first MS like symptom in 1991 and did not have any symptoms for another 8 years. Had I been correctly diagnosed at that earlier time, I feel quite strongly that some simple changes may have greatly postponed the problems that I now have to deal with on a daily basis (heat sensitivity, neuropathic pain in my foot and leg, vision problems, fatigue, and loss of balance). The changes I would have like to have made are the one's that I'm following now which I use to complement the Avonex I've been taking for the last 5 years. I would suggest reading through many of the excellent posts in the Diet and Natural Approach forums to get an idea of what other folks have tried. So far, I've eliminated a few proinflammatory things such as garlic and partially hydrogenated fats. I'm also taking cod liver oil, omega-3 fish oil, ground flax seed, r-lipoic acid (an antioxidant), vitamins E and C, and green tea which all provide some anti-inflammatory benefit. I'm also looking into n-acetyl cysteine and turmeric though I'm still in my research phase on these two.
I just got married this summer (July - annoying taking Rebif on my honeymoon....oh well) and we are thinking of kids soon. Has anyone else went off Rebif for planned pregnancy?
It's best to stop any Ifn-B use during pregnancy. There was a recent post linking to an article
which discussed complications which can arise from it's continued use during pregnancy.
Best wishes, NHE