Hi, I've been on Rebif for almost two years. (started March 04).
It's kind of like "what comes first, the chicken or the egg". I was borderline hypothyroid before starting Rebif. Then for the last year and a half, my TSH levels were all over the place.
I have 75's, 88's, and 100 doses in my cabinet. My family Dr. keeps a close eye on it, with levels done every three months.
He said that my metabolism is all over the place, partly due to taking Provigil, Rebif and etc.
Finally, in December 05, my TSH was in the normal range with a dosage of 88 Synthroid.
So, back to the quote. My mother was hypothyroid, started in her late 50's. From what I understand, this can run in families. I also started having slightly hypo. test results in my late fifties.
Did the Rebif cause the crazy ups and downs for the last year and a half?
I think it was certainly a factor. The literature with the med. states caution if you have thyroid disease. But-------I was already starting to be hypo. before being diagnosed with MS. Would my levels have gone crazy without the Rebif? MS Specialist says yes. PCP says maybe!
I have done very well on the Rebif. No new lesions in two years. For me, the thyroid issues can be addressed a lot easier than progression of the MS.
Best Wises, Bobble43