I started taking Rebif in June of this year, immediately following my diagnosis. About one month in, I noticed that I was retaining water ALOT, I also had an increase in hot flashes and being hot all the time. I am 47 so assumed it was menopause, added hormones to my pharmacy run, then I developed high blood pressure which could be explained by my age and genetics (everyone in my family has hbp). Now, the water retention has continued and I have noticed that I can't seem to get enough sleep, and well just feel AWFUL! I have an appointment with my PCP for a blood work up, but wondered if anyone has ever experienced this? I decided to try an OTC thyroid med with the active ingredient L-Tyrosine. I immediately noticed an improvement with fluid retention and energy level, it's difficult though becuase if I take too many my heart races. If you are taking thyroid meds, what are you taking and how has it worked for you?