Well - Some initial reactions (having finished all my Avonex and taking 2 Rebif injections)
My initial reaction to the Rebif syringe - is - Hey, what's up with this funny little toy needle.... Folks who have been doing Avonex are going to like this part. The glass syringe is pretty doggone difficult to manage to push in the plunger as there isn't much to hold on to. That green thing they sent to help hold the syringe doesn't. I haven't tried the Rebiject thing and am not sure I want to....
I also don't like the packaging of the syringe compared to Avonex. The Avonex syringe packaging has a big hole in it, you can stick your finger in there and open it with ease. For Rebif -- there's this tiny little corner you have to pick with your fingernail. If you have a lot of spasticity or other 'touch' problems I could see where this could be even more difficult than it is....
As far as the injection - yes - it does burn a tad (but I'm only doing 8.8 mcgs now) which never happened with Avonex - I supposed because it was so deep in the muscle. I'm sure it's probably going to burn more as we increase the amount and the concentration.
Jury is still out on how 'poopey' I feel the day after the injection. It may take two months to find out. One month to ramp up to 44 mcg and another month at that concentration to see how I'm feeling each day.
I'm learning to breathe under water. It's quite beautiful down here.
I used to think that if I tried, I would drown.