Hey, G. I started on Copaxone, then went to Avonex, then Tysabri (before it was pulled) then back to Avonex, then Rebif. I stopped on Oct 12 of this year, and am doing nothing. I have an entire titration box of Betaseron in my closet, cause my ins. wouldn't allow it before I did Rebif. I also have an entire box of Rebif 44 in my fridge. Just threw away a half box of Avonex, felt like it was sacrilege, I' m going to hell or something. I have to have my LFT again beginning of Nov to see, but they mailed me the info on 3 diff oral trials. In theory, after doing shots for 7 years a pill would be AWESOME, but the side effect list is SCARY!!! Serono told me if the AST and AFT ever get to 5 times normail, you can not re-do Re-bif! I am at 3 times normal. I asked her at what point am I doing irreperable liver damage, that's when she told me 5 times normal level, and you're cut off. I have often wondered aloud, If I have had ift for 17 years, mild, with very slight progression, the MS MAY put me in a wheelchair, but the meds could kill me!!! My husband just says " You have to do the medicine for the kids ( 6 and 4), but he doesn't realize how much It does stink!! I'll go to put my Rebif shot in my upper arm, and he walks by and winces audibly!! I'm like come on, wuss!! Our life ins. co. sent out a nurse (pre dx) for blood draw, he had to lay on the couch cause she was fishin in his arm!!!