As you can see from my signature, I have finished taking antibiotics after four years, one year full-time and three years intermittent. I have never had any return of symptoms in the gradually lengthening periods when I haven't been taking them and in fact I have had no MS episode since starting, compared to the constant and rapid progression with the odd relapse thrown in for good measure before I started. I have been thinking about this since early June, when I last took any doxycycline and the rest. All the times between taking antibiotics I am still seeing subtle improvements, as though my own immune system has taken charge, so there seems very little reason to fill myself up with antibiotics without good reason. David had already finished his treatment but he left it up to me to decide I was going to do the same. If he had thought it was a bad idea, as a microbiologist who has also trained in neuropathology, he would have stopped me.
It seems to be a fact that people with MS don't tend to have an enormous bacterial load compared to people with arterial disease or fibromyalgia, say: it just knows where to hide away to cause the most damage. I really had not experienced any reactions on taking metronidazole , other than depression, since about nine months into treatment. The biggest reaction was actually at about six months, just before my first follow up scan and just before starting rifampicin. All I experienced with that was the sudden lessening of the immunomodulation that I had with taking both doxicycline and roxithromycin. Before and throughout I never had raised blood pressure, sticky blood, altered thyroid levels, rheumaticky aches and pains or anything which many other people seem to experience.
Yet I till have an EDSS of two. So some tracts of myelin still need either to be rebuilt or a way round them found. That will take time, but it won't come any quicker by throwing antibiotics at the areas.
I think I will start a topic very soon, marking my post-abx improvements. This would seem to make sense because it might show to people that there is no reason to carry on, 365 days a year, until every tiny deficit is gone.
An Itinerary in Light and Shadow Completed Dr Charles Stratton / Dr David Wheldon abx regime for aggressive secondary progressive MS in June 2007, after four years. Still improving with no relapses since starting. Can't run but can paint all day.