12 people is still a very small study. Hopefully, they will be able to isolate the beneficial chemical cocktail that the worms are secreting that modulates the human immune system. That way, MS patients could potentially have the benefits without the risks associated with having independent minded worms crawling through us.
Yes it is a small study and if I'm not mistaken only four of the entrants had problems requiring them to take anti-helminthics, which this second study/observation is based on taking the numbers even lower.
I've had a couple of computers die in the time since and long ago lost the record of our correspondances but a few years ago I had the pleasure of corresponding with William Harnett of the University of Strathclyde, who along with his wife Margaret at the University of Glasgow who by far were the earliest and by far have done the most work in isolating the chemicals and proteins that helminths utilize to control animal/human immune systems. They long ago isolated ES62 (excrete/secrete) from the filarial nemotodes, which happen to be particularly obnoxious helminths. At the time of our correspondance Dr Harnett didn't know of reasons to consider that the excretions/secretions of other helminths would be drastically different than any other helminth that has evolved to survive in humans.
The Harnett's work is a work in progress admittedly. No one claims that ES62 constitutes the entirety of the impact on the human immune system or that it is the complete chemical/protein package of what fllarial nemotodes secrete/excrete nor that it's exactly the same as the multitude of other helminths excrete/secrete.
This is only the first thing that came up, they've done a ton of work on this since.....going from memory I think he said 1965 http://onlinelibrary.wiley.com/doi/10.1 ... 400.x/fullhttp://onlinelibrary.wiley.com/doi/10.1 ... 400.x/full
My Cousin is doing his Phd at Cambridge in Medical Biochemistry and whilst not strictly his field he reckons isolation and commercialisation of the compounds involved is decades away.
In the meantime if you believe Helminthic Therapy works then 5 years treatment will cost about the same as 3 weeks Copaxone