I just posted this in the Antibiotic forum, tells most of my story:
2005 I suffered from extreme fatigue - hadn't really felt good in several year..... passed it off to life stress, etc.
I developed patchy blindness in both eyes. MRI revealed 20 brain lesions (3 active & angry), & 1 spinal lesion. Spinal positive for OCB. Methyl Malonic Acid (assoc. w/B12 deficiency) was sky high (>550). They gave me IV Steroids for 5 days and started me on Copaxone (they recommended Avonex but I chose Copaxone).
I researched online and found the "Best Bet Diet" and began that strictly (continued that for 9 months without any "cheating") - also started an extensive regimen of supplements and vitamins.
Eyes recovered after 4 weeks of being unable to drive or read.
I developed severe tingling in my lower legs and lower arms (stocking-glove), a night I would wake with my entire body buzzing, and my left hand began to lose strength and function. I continued to have debilitating fatigue.
Some improvement with the diet, began Naltrexone (LDN) at the recommendation of my Neuro to try and stop the tingling which was driving me mad. Fatigue very high. Quit Copaxone due to multiple site reactions and minimal improvement.
Some improvement in the tingling - had read about abx at this point and talked to Neuro and after signing a waiver, he agreed to prescribe.
Doxycycline 200mg - Fluish reaction, felt yucky, subsided within a week or two.
Started Azithromycon 250mg - don't remember much reaction.
Began to feel better finally - fatigue lessened, mental fog cleared very quickly.
Started Metronidazole 500mg - Ahhh man within an hour of taking the first pill thought I was going to DIE. Had to stop after 3 days of being unable to get out of bed for more than an hour at a time, felt utterly poisoned. Excessive clear nasal discharge, night sweats, chills - YUCK.
Continued pulses of Metronidazole - 5 days at a time, once a month.
So it has only been 2 years since diagnosis... but I haven't felt well for probably 5 years - and as a teen I was diagnosed with Chronic Fatigue Syndrome - which I'm wondering if it could have been the start of a Cpn infection?
I will continue to take LDN - as it boosts endorphins/fighter cells... and that walks hand in hand with the Cpn theory.
Not sure how long I will continue the Abx - but it most definitely was at least a year before all of the tingling disappeared - and only the past 6-8 months that I have felt the level of energy I now have....
Last year I couldn't garden or walk for long periods without paying for it for days.
Honestly - I feel better than I have in at least 6 years or more...
Dx MS 10-05, multiple symptoms. MRI 20 brain lesions (3 enhancing), 1 spinal lesion, positive spinal, MMA>550.
Started: LDN 12-05, Wheldon CAP: Doxy 2-06, Azith 3-06, Flagyl 5-06.
Now: All is well, no symptoms! 4/2010