heya, anything is dangerous in excess. luckily I don't take over 450mg of zinc per day, equivalent for me to the daily amount that was harmful in EAE mice. it's about finding the sweet spot.
can you link me up to the studies that show zinc excess is a problem for ms patients? i wouldn't mind checking that out. or are you still referring to the 2004 book?
an fyi for when you get the zinc lab work done.. regimens-f22/topic2489.html
"The first thing to understand when beginning nutrition investigations, is the unfortunate language of the lab. Specifically, the term 'normal'.
As described briefly above, the 'normal' range is often quite a broad range which in many cases includes both sick and healthy people.
There is a much smaller range within the normal range that can be described as 'optimal'.
For example, at one lab i'm aware of, the normal range for zinc is given as 10-20 umol/L. at an infectious disease clinic, the normal range for tests done there was 9-14 umol/L. the WHO's reference range is 11.5-18.5 umol/L. ms patients average in the low teens. healthy controls average in the high teens, with high end healthy levels sometimes over 20. an example of toxicity in research involved levels over 36."
: aim for 18.2-18.4 umol/L. (120 ug/dL) i have not firmly established this upper limit but i would say go no higher than 20 umol/L. the test is just serum zinc.
at my first zinc test my level was 8.6 umol/L. [update: found a study of children with healthy controls averaging 20.5 umol/L serum zinc]copper
: aim for 100-114 ug/dL or 17.3-18 umol/L. NB zinc supplementation should always be balanced with copper. detailed copper info here general-discussion-f1/topic19529.html#p188525magnesium
: aim for .91 mmol/L. (or 2.2-2.3 mg/dL). 'normal' range in SI units is 0.70-1.10 mmol/L. research says anyone below 0.90 should be supplementing. some sources say minimum 0.95 mmol/L. i even found one study where the healthy controls average was 1.1. the test is just serum magnesium (see below)."
my approach: no meds so far - just nutrient-dense anti-inflammatory whole foods, and supplements where needed
info: www.whfoods.com, www.nutritiondata.com