ah I found it - here's the link for any interested readers. the zinc details are on p. 94. http://books.google.ca/books?id=g9fuxaV ... nc&f=false
the murine EAE study referenced dosed the mice with the equivalent of 450mg zinc daily to induce harmful effects. do be careful never to take that much!
the book linked above limits its recommendation to 10-15mg per day (see top of p. 94).
standard recommendations for ms patients are on the order of 25-50mg per day. (eg 'best bet' recommendations)
missing from the book: at present the upper limit recommendation for healthy men and women is 40mg/d http://www.hc-sc.gc.ca/fn-an/nutrition/ ... bl-eng.php
so much for practice. meanwhile in research, the upper limit is actually 50mg/dhttp://jn.nutrition.org/content/130/5/1344S.full.pdf
"Currently this is commonly considered to be a total of 50 mg elemental zinc per day for adults"
again, I would emphasize healthy adults.. my doc prescribed 100mg/d in the short term (1 month) to address deficiency.
anyway j, you are welcome re the vit E
re the uric acid you only have to get to 5 - but as you know I think your low-ish ua level is an indicator of your low zinc status so 'nough said.
going back to the magnesium - any plans there, given the intake of supplemental vit d3?