This Is MS Multiple Sclerosis Community: Knowledge & Support

Thinking of adding Padma basic to my regimen. Any thoughts on whether it is likely to interact with:

Circumin
Fish oil
Evening primrose oil
Walnuts
Vit D3, E, B12
R-Alpha lipoic acid
Inosine
Copaxone

Thanks,

Jim

Thanks..to..much..

jim just a question - have I already asked you what form of vit E you are using? also depending on the size of that d3 dose you may want to consider measuring/testing your serum magnesium level (i'd suggest serum zinc too, but I know you have that result coming in today anyway!)

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my approach: no meds so far - just balanced whole foods (partial 'paleo', much less outright elimination), science, supplements, & bloodwork
my regimen - www.thisisms.com/ftopict-2489.html
www.whfoods.com, www.nutritiondata.com

Zinc was 80 (don't have units in front of me). UA was 4. Don't know what form of vitamin E. taking 400 IU per 3 grams of PUFAs.

Good cholesterol was obscenely low (20). Doc suggested adding niacin. Creatinine also low.

80! that's rough. aim for 120 if you can. when supplementing with zinc, do be sure to balance with copper. solaray has a decent zinc copper product, zn:cu 50:2. fyi in this rat study zinc deficiency lowered hdl ('good') and raised ldl cholesterol.
Effect of dietary zinc deficiency on hematological and biochemical parameters and concentrations of zinc, copper, and iron in growing rats
http://www.ncbi.nlm.nih.gov/pubmed/11567779

UA 4 - that looks roughly like an MS remission sort of value. is that a baseline number? or after some inosine?

with vit e be aware that alpha tocopherol on its own can be trouble. some are synthetic. the SELECT study demonstrated that driving the natural ratio out of balance with supplements using a single fraction (ie synthetic alpha tocopherol) at the expense of another (gamma tocopherol) can lead to increased cancer risk.

regimens-f22/topic2489.html
"vitamin E - choose a natural source natural ratio E8 complex, with 4 tocopherols and 4 tocotrienols. note: you don't want just alpha tocopherol, or 'mixed tocopherols'. "

_________________
my approach: no meds so far - just balanced whole foods (partial 'paleo', much less outright elimination), science, supplements, & bloodwork
my regimen - www.thisisms.com/ftopict-2489.html
www.whfoods.com, www.nutritiondata.com

4 is the "before" number. Started the inosine the day after I gave the sample. Thanks for the tip on the vitamin E, probably the bad one as it was cheap. You'll recall that you and I agreed to disagree on zinc supplementation. I don't want another round of papers cited. It suffices to say that I think zinc poses more risk than benefit to MS patients. I'll leave low-normal alone for now.

oh yea, what was the name of that book again?

_________________
my approach: no meds so far - just balanced whole foods (partial 'paleo', much less outright elimination), science, supplements, & bloodwork
my regimen - www.thisisms.com/ftopict-2489.html
www.whfoods.com, www.nutritiondata.com

ah I found it - here's the link for any interested readers. the zinc details are on p. 94.
http://books.google.ca/books?id=g9fuxaV ... nc&f=false

the murine EAE study referenced dosed the mice with the equivalent of 450mg zinc daily to induce harmful effects. do be careful never to take that much!

the book linked above limits its recommendation to 10-15mg per day (see top of p. 94).
standard recommendations for ms patients are on the order of 25-50mg per day. (eg 'best bet' recommendations)

missing from the book: at present the upper limit recommendation for healthy men and women is 40mg/d
http://www.hc-sc.gc.ca/fn-an/nutrition/ ... bl-eng.php

so much for practice. meanwhile in research, the upper limit is actually 50mg/d
http://jn.nutrition.org/content/130/5/1344S.full.pdf (2000)
"Currently this is commonly considered to be a total of 50 mg elemental zinc per day for adults"

again, I would emphasize healthy adults.. my doc prescribed 100mg/d in the short term (1 month) to address deficiency.

anyway j, you are welcome re the vit E

re the uric acid you only have to get to 5 - but as you know I think your low-ish ua level is an indicator of your low zinc status so 'nough said.

going back to the magnesium - any plans there, given the intake of supplemental vit d3?

_________________
my approach: no meds so far - just balanced whole foods (partial 'paleo', much less outright elimination), science, supplements, & bloodwork
my regimen - www.thisisms.com/ftopict-2489.html
www.whfoods.com, www.nutritiondata.com