This Is MS Multiple Sclerosis Community: Knowledge & Support

immunomodulatory effects of salbutamol...but it was probably the vasodilation response

ratio of cell migration mediator MMP-9, and its inhibitor, TIMP-1 were assessed in the culture supernatants. Quercetin reduced, in a dose-dependent manner, the proliferation of PBMC and modulated the level of IL-1beta and TNF-alpha released by PBMC in the culture supernatants

Clinical studies indicate that buckwheat tea, which contains
high amounts of rutin (quercetin) is useful in the treatment of chronic
venous insufficiency (CVI).9 A German placebo-controlled,
double-blind study showed that treatment of CVI withbuckwheat herb (Fagopyrum esculentum) tea is safe and
could prevent further leg edema development in patients with
CVI.9

Increased concentrations of serum TNF-α, an inflammatory marker, were found in women who had insufficient vitamin D levels. This study is the first to find an inverse relationship between vitamin D levels and concentrations of TNF-α in a healthy, non-diseased population. This may explain the vitamin's role in the prevention and treatment of inflammatory diseases, including heart disease, multiple sclerosis and rheumatoid arthritis.

"The findings reveal that low vitamin D levels negatively impact inflammation and immune response, even in healthy women," said Catherine Peterson, assistant professor in the MU College of Human Environmental Sciences. "Increased inflammation normally is found in people with obesity or chronic diseases; a small decrease in vitamin D levels may aggravate symptoms in people who are sick."

Bromelain is a mixture of protein-digesting (proteolytic) enzymes found in pineapples (Ananas comosus ). Pineapple has been used for centuries in Central and South America to treat indigestion and reduce inflammation. Bromelain, which is derived from the stem and juice of the pineapple, was first isolated from the pineapple plant in the late 1800s. It is approved by the German Commission E to treat swelling and inflammation following surgery, particularly sinus surgery.

Bromelain can be useful in treating a wide range of conditions, but it is particularly effective in reducing inflammation associated with infection and injuries.

cheer - Of all the items you list on your endo program i don't use Salvia i thought there was only the psychodelic type (i lived thru the 70's want to live now) and i have read there is a different type. What does this do and where do you get this so i may ad this to my regimine.

have you heard of butchers broom an herb to help circulation? I am adding that to my collection..

This is the first study in humans to investigate the association between markers of exposure to ambient air pollution and the progression of CIMT (common carotid artery intima-media thickness), an accepted measure of the progression of atherosclerosis [26], [27]. CIMT results from the cumulative atherogenic processes that occur in the artery wall. As such, CIMT progression is associated with future clinical cardiovascular events [26], [28], [29]. Our data indicate that the progression of sub-clinical atherosclerosis correlates with home outdoor air quality, with particularly strong associations among those living along highways. Southern California highways have exceptionally high traffic density (i.e. several hundred-thousand vehicles per day) – several fold higher then on main surface roads – and most highways are designated truck routes. Moreover, trucks are the key source of diesel particles while passenger cars operate primarily with gasoline in North America.

Bernhard Juurlink published a hypothesis in 1998 that MS is related to decreased blood flow in the brain and spinal cord.

"It was very difficult to get anyone interested in this idea — the idea was easily testable by, for example, looking for blood flow in white matter in MS patients," Juurlink said in an interview this week. "I tried to first interest clinical colleagues to image brains of MS and non-MS patients, to look at blood flow, with no success."

Oxidative stress can be minimized by 1) maintaining reduced-glutathione levels through the administration of cysteine precursors such as N-acetylcysteine and 2) limiting neutrophil invasion by administering platelet-activating factor antagonists such as BN 52021. Aggressive nutritional support following CNS trauma can also contribute to maximizing antioxidant defenses. Furthermore, we suggest that flavonoids such as quercetin have the potential to be therapeutically effective because of their free radical quenching, iron chelating, and anti-inflammatory properties.

(bold emphasis mine)