Welcome to the forum and I'm really glad you joined. Because long term suppression has been medically accepted for so long, most people are convinced that is the "safe" way to go. The truth of the matter is that suppressing is just what it sounds like, dampening, slowing down, weakening the immune system and that doesn't have the capability to "cure" the disease.
I think it's been shown that the bone marrow isn't responsible for the multiple sclerosis process, meaning that a high dose of an immune suppressant (Cyclophosphamide) over a short period can eliminate the faulty immune system and let the bone marrow create a new, healthy immune system (Revimmune process), yet not leave the recipient susceptible to dangers like PML which require over suppression over a longer time.
In other words, it seems that high dose, short term, is safer and offers the chance of actually eliminating the disease, whereas the only thing long term suppression has in it's favor is that it's medically accepted and covered by insurance.
HiCy wrote:Don't take offense to the Tovaxin comment.
I appreciate you saying that Brett and it was clear that it was the doctor's opinion and not yours. It probably sounds overly smug, but when it comes to MS I've learned not to put much stock in doctor's opinions!
I have great hopes for the revolutionary new idea of "rebooting" the immune system, which at this time happens to be using high dose cyclophosphamide and Campath 1h. I imagine researchers will eventually develop substances which more specifically eliminate and let regrow ONLY the factors involved in the MS process, which will result in shorter and safer recovery times.
Tovaxin, on the other hand, eliminates specifically the IDENTIFIABLE T cells involved in the MS process, which is a marvelous improvement over simple suppression but, if Tovaxin has a downside it is that it has no effect on the B memory cells, the cells responsible for "remembering" myelin as deserving attack.
This situation means that Tovaxin has to be readministered periodically. In that light, there is no clear danger involved with Tovaxin. In the 50% of those with MS whose mrtc's can be identified Tovaxin has shown to be almost 100% effective.
If Opexa researchers are ever able to approach 100% in identifying responsible mrtc's, and if they are ever able to identify and eliminate the B cells responsible for the reciprocation of the MS disease process, that would be the ultimate and most preferable solution to MS.......an effective, one time MS treatment without danger of long term risk.
HiCy wrote:It is really an issue of what works and what doesn't. Everyone is different and some treatments are not for everyone so the more that is available the better. I have been on everything over 13 years and so the Revimmune solution was the next option to fight this disease.
This really is the "old west" days of MS treatment in which people entering into experimental treatments can as easily face danger with no benefit as face a cure. Out of all the things out there currently, I'm convinced you got into the right one and I'm just absolutely convinced you won't be sorry. Cyclophosphamide has been around since the 1950's, so it isn't that you're dealing with a substances which long term history is unknown and that alone is worth a lot.
Again, thanks for joining, this is going to be interesting!