I think the normal rituxan infusion schedule for ms is 1000mg on day 1 and another 1000mg 2 weeks later. This is repeated every six months or so for up to two years.
The infusions were pretty uneventful affairs for me. You just sit and visit with your fellow inmates for four or five hours while it drips away. They can unhook you to go to the bathroom...so you don't have to drag the ball and chain with you. Nurses check your blood pressure and temp regularly. Some people have reactions and get additional Benadryl so they get sleepy. I didn't have any significant reactions and didn't get at all sleepy. Bring drinks, snacks, and something to keep busy that doesn't require a lot of focus. Magazines and crosswords kept me busy during the little time there wasn't conversation going. I tried starting a book several times and couldn't get into it.
Hope that helps.
Are you jcv+? That would be something to worry about with rituxan.