I did an aggressive course of rituxan so this might not translate to your situation well. I did become iron deficient and lost a lot of hair. It's been around 300 days since first infusion and my hair, previously a little wavy, is now much more wavy. Weird. Other than that, I think I only got a little tired after infusion day...and completely exhausted from iron deficiency later.
Good luck. Rituxan is good stuff.
Edit: re-read this after the thread got bumped. I think my rituxan side effects paled in comparison to my valtrex side effects so I completely forgot the minor rituxan issues. I did have more than fatigue in the days after my infusions, like worsening of sensory symptoms (which were easily managed with Benedryl) and night sweats. There are probably more side effects detailed in my rituxan thread. People getting the standard ms protocol usually don't experience these though.