Had my first infusion of Rituxan yesterday at UCSF. Had a slight infusion reaction about two hours in that resulted in nothing more than a very itchy throat. They cut the flow, added more Benadryl, and we started again about 20 minutes later. Because of this hiccup whole infusion lasted about 7 hours.
After several denials my insurance (Blue Shield of California) agreed to pay for it thanks to a letter from my neurologist, Dr. Okuda. He had first wanted me to go on this stuff some two years ago when he recommended I stop Tysabri, which was not slowing down my progression adequately enough. We were denied and I tried Cytoxan, but it had little effect.
As a young person (34) with some evidence of active disease on last MRI I hope that I fall into the group that saw some clinical benefit from Rituxan http://www3.interscience.wiley.com/jour ... 7/abstract
Next infusion in two weeks. I'll update my progess, which will hopefully be no progression.