I'm the one who voted for acetyl l carnitine (ALCAR), but didn't think I could give you much info because I'm a "newbie"
On Avonex 3 mos., and at this time I am only taking 1/4th the recommended dose in the study (1 500 mg pill a day).
I've had a lot going on and can't really say if the ALCAR is making me less fatigued.
About 3 days after I started compounded HRT, ALCAR and alpha lipoic acid (both on pharmacist's recommendation when I picked up the HRT), my neurologist
shocked me by putting me oral steroids when I called to report my first relapse.
It's anybody's guess what's contributed to my feeling better.
I think the alpha lipoic acid is helping numbness, burning, tingling and MS hug of my left leg.
I'm also more alert and walking better (my worst symptom).
As a newbie it looks like I could end up taking a lot of drugs for a lot of different symptoms at some point, so I'm trying hard to stay away from anything but the Avonex until I have too.
That's the reason I'm sticking with ALCAR for now. My pharmacist recommended it as "neuroprotective" and then this study came out.
Hope this helps. Let us know what you decide and if it works.
I find this whole MS stuff to be mind boggling at best