CVfactor wrote:For the non-myeoblative procedure, what is the recovery like? I know that with the myeoblative it is very critical to maintain sanitary conditions since you basically have no immune system after the procedure.
If the non-myeoablative method is less risky as far as post infection, this would probably seem like a more marketable option for people in the early stages of the disease.
Perhaps this graph may help to visualize the recovery profiles (although being in a clean environment during neutropenia is important with both protocols, perhaps a little more so with the myeloablative protocol due to longer average duration of cytopenia). . . .
http://2.bp.blogspot.com/-abM0YFUDhtQ/T ... rofile.jpg
The reason the line is dotted for the non-myeloablative HSCT protocol is because the total immunoablation will differ somewhat from patient-to-patient. This is also why it is a more difficult protocol to administer as opposed to the myeloablative (BEAM) HSCT protocol that does not have substantial variation from patient-to-patient.
If recovery timeframe were the only important factor to consider, I would opt for the non-myeloablative protocol. However, if other factors like treatment cost, treatment facility selection and confidence-in-efficacy are important, then one may opt for the myeloablative protocol as I did.