So, 10+ more years
. Think it is better to do it now, rather than wait. In 10 years who know what will happen with your MS
This is the way that all the drugs go through to get approval. HSCT is not a cake walk. It has an approximately 70% of success rate with a high mortality rate of 2-3%. Patients undergo a 'conditioning' chemotherapy regimen that heavily suppresses or even wipes out their effective immune system.
It is not known which groups of patients benefit from the treatment. It is not known whether renewal of inflammatory disease activity will occur in the long run. Also not known what will happen with the neuro degeneration process which seems to be independent from deregulated immune cells and it is a characteristics of the progressive stage. This process might start 15 or 20 years after the onset of the disease. There is no such a long term data available at the moment.
It is not a coincidence that currently, neurologists are not recommending HSCT for those RRMS patients who are doing well (even though they would benefit the most from the treatment) and responsive to drug treatment.
Chemo has lots of serious long-term
Reduced lung capacity
Increased risk of other cancers
”Chemo Can Actually Cause Cancer”
Monday, August 6, 2012 6:59 AM
”Researchers in the United States made the "completely unexpected" finding while seeking to explain why cancer cells are so resilient inside the human body when they are easy to kill in the lab.”