I agree, hats off to Ladymac. Great advice all around. It can be overwhelming if you live your whole life around MS related things, so deciding on the best meds for each person & doing the best you can is the only way to go. I am glad I pushed through a rough start with Tecfidera & am doing much better now. I feel for those who had severe reactions and had to discontinue it, that is so disappointing. We should all give ourselves a pat on the back for staying positive through this MS journey.