Anyone knows about BG12 and SPMS?

Discuss Tecfidera (BG-12, dimethyl fumarate) as an oral treatment for multiple sclerosis.

Anyone knows about BG12 and SPMS?

Postby xpsychiatricmd » Tue Mar 19, 2013 5:07 pm

With BG12 likely to be next the next MS drug to be approved, any information about its effect on SPMS?
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Re: Anyone knows about BG12 and SPMS?

Postby centenarian100 » Tue Apr 16, 2013 1:26 pm

The two major phase III trials yielding drug approval by the FDA (CONFIRM http://www.ncbi.nlm.nih.gov/pubmed/22992072 and DEFINE http://www.ncbi.nlm.nih.gov/pubmed/?ter ... ate+DEFINE) were both on patients with relapsing remitting multiple sclerosis.

I couldn't find any data on progressive forms of MS. Let me know if you come across anything.
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