I found this thread after taking my first dose of Tecfidera on September 6th.
I had eaten a bowl of oatmeal for Breakfast & took Tecfidera a half hour after I ate. No Aspirin. Turned in to an itchy lobster, which made me come to the internet looking for more information about how to minimize the side effects. Found this thread almost immediately.
For my 2nd dose that night, I took 162 mg of Bayer an hour before Dinner and took Tecfidera in the middle of the Meal. It was like night and day from the first pill that morning.
I'm halfway through my 2nd week and symptoms have been really mild for the most part (thanks to this thread). Halfway through the first week, the symptoms were so mild as to be almost unnoticable. I was expecting all hell to break lose when starting the 240mg dose of Tecfidera but it was similar to the beginning of the 120mb dose - mild symptoms.
Had a little problem today as I forgot my Jimmy Dean Breakfast Sandwich when I went to work. I get the one with Egg Whites and Turkey Sausage. Since I didnt have it, I had to go buy breakfast. They did not have Turkey Sausage and I did not want to use regular Sausage, so I substituted Ham. Big mistake. The Fat Content in the Ham was much lower than the Turkey Sausage and it really made a difference. When the Flushing kicked in, it was much more severe than it had been since that first pill. And it brought with it a lot of nausea. Spent a couple of hours feeling like I was gonna puke. Not fun. Tried Green Tea and Rice Cakes to help settle my stomach. They helped temporarily but then it came back. I'm gonna have to keep a spare Breakfast sandwich in the freezer at work so this doesnt happen again.
Hoping to cut the Aspirin down to 81 mg at the start of the 3rd week and also hoping to eliminate it altogether, eventually.