Had to stop this drug 6 days in... I couldn't take the side effects. Severe cramping and abdominal pain, sweating, constipation, nausea and vomiting, and explosive diarrhea. I never made it to the 240mg dose, but for those that have, I hear they are happy. I wish so very much I could tolerate this drug, but after my experience...Rebif is looking like a heavenly choice (Never ever thought I would say that) Good luck and I hope your husband feels better.