I started on Tecfidera in July and for the first 3 1/2 weeks had no problems except for some occasional flushing. Received my first refill and started having stomach problems, nausea, diarrhea and vomiting. At first it was about 5 hours after taking the meds and then it would subside. However, gradually it got worse where I felt terrible all the time. Finally my neuro took me off the meds. Its been a month now and I feel much better. Now my neuro wants me to try again but start very slowly.....120 mg 1x/day for 2 weeks, then 120 mg 2x/day for 2 weeks, then 120 mg 1x/day and 240 mg 1x/day for 2 weeks and finally the full dose. Its making me a little nervous because I felt so terrible before but I hate the thought of going back to injections.
Is anyone else trying to ease onto Tecfidera this way and if so, how is it working out?