While nothing can be considered factual about a treatment until it's officially approved, it seems that Tovaxin is 100% effective, or close to it, and it hasn't shown any risk factor. The only risk I can think of might involve a lab mistake but you accept that risk with any treatment.Isn't this everything all of us Tovaxinites have been chasing?
Although the absolute proof will be in hindsight after many years, at this point it seems that removing the myelin reactive T cells ends the MS disease process about as precisely as possible and for that reason really has no suppressing effect.
The only reason I mentioned the consideration of "resetting" the immune system in your case is because the Tovaxin clinical trial requires a year of possibly being on placebo. If someone has very aggressive disease, going "naked" for a year might not be the best option and the consideration of a very aggressive treatment is more easily justified.
I personally haven't investigated the situation but in a legitimate case of extremely aggressive MS there might be an option of resetting treatment off label somewhere. Stony Brook is where they've been doing the work with high dose cyclophosphamide and I don't know if it's possible to be treated there or maybe squeak into some kind of open label study?
I don't know the exact differences between the actual treatments but for some reason losing your hair is a factor with high dose cyclophosphamide and not with Campath, although increased rate of autoimmune thyroid problems have been associated with Campath and not with high dose cyclophosphamide.
Of course there are other long and short term risks involved with both of these treatments to be considered.