Well I'm number 65 on the Revimmune list. Lets hope it doesn't kill me!
The only drug I saw or have seen any "improvement" in symptoms is LDN. If I forget to take it I shake. I've tried it more than once and have forgotten to take it and it does not take me long to remember why. I'm not kidding either.
Folks, the difference between SPMS, RRMS, PPMS, is MRI activity. RRMS shows the most MRI activity, which is why they use it in studies. SPMS is where the lesions start to lesson and disability really starts to kick in. PPMS, the lesions are gone and unfortunately the atrophy starts in the CNS. This where there are many "black holes".
This is how the doctors at the Rocky Mountain MS Society explained it to me. Considering these folks have like 150 books on MS I figure they got a good grip on definitions