Natalizumab in pediatric multiple sclerosis

A board to discuss the newly-released drug Tysabri, (formerly known as Antegren) as a treatment for Multiple Sclerosis

Natalizumab in pediatric multiple sclerosis

Postby MSUK » Fri Feb 15, 2013 4:51 am

Natalizumab in paediatric multiple sclerosis: results of a cohort of 55 cases


BACKGROUND: Limited information is available on the use of natalizumab (NA) in pediatric multiple sclerosis (ped-MS) patients.

OBJECTIVE: The purpose of this study was to describe the long-term effects of NA in a large cohort of active ped-MS patients.

METHODS: Patients with definite ped-MS were treated with NA if in the previous year they had experienced at least two relapses or a severe relapse with incomplete recovery while on immunomodulating treatment, or at least two relapses and new magnetic resonance imaging (MRI) lesions regardless of any prior treatment.... Read More -
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