Early development of anti-natalizumab antibodies in MS

A board to discuss the newly-released drug Tysabri, (formerly known as Antegren) as a treatment for Multiple Sclerosis

Early development of anti-natalizumab antibodies in MS

Postby MSUK » Thu Jun 20, 2013 12:30 am

Early development of anti-natalizumab antibodies in MS patients

Abstract

The purpose of this study is to monitor the development of anti-natalizumab antibodies to evaluate their first appearance in multiple sclerosis patients, since their presence has been associated with a reduction in the efficacy of the treatment and an increase of adverse events...... Read More - http://www.ms-uk.org/index.cfm/tysabri
MS-UK - http://www.ms-uk.org/
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Re: Early development of anti-natalizumab antibodies in MS

Postby HarryZ » Thu Jun 20, 2013 7:06 am

Hmmm...almost 16% of Tysabri patients found with the drug's antibodies within the first couple of month's treatment and only now are they suggesting careful monitoring should be done during this time!!! Surely this monitoring had to have been done before this report was released...I hope!

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