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I had my 2nd infusion last week and I definately notice the difference in my symptoms.
After the first infusion, I had one great week of symptom relief. I went from about an 8 on the scale of symtoms and pain to about a 4. But as I said, it only lasted a week.
So I went to my 2nd infusion hoping for 2 good weeks. I didnt get the definitive relief, but I can honestly say I notice an overall improvement of my symptoms. I haven't needed my cane in over a month. I think tysabri is going to be awesome for me!