I'm sorry for both of you in having poor results with Tysabri. I had less than stellar results with AC&R. My neuro doesn't even suggest Tysabri for me. I can see me having unpleasant side effects too somehow. I think if there's a chance of a weird or unpleasant side effect, it's going to happen to me. In my case, it really does seem as though the treatments makes the disease worse for me, IVSM included.
If I don't stay in the Tovaxin trial, then I might be taking a break from the meds for awhile. That's an option the doctor suggested I think about. ...Especially since I had an unremarkable MRI last week (and I have been off meds for two months.)
Take care, Ewizabeth Previously Avonex, Rebif & Copaxone RRMS ~Tysabri, 31 infusions, ended 9/09. Starting Copaxone 12/09, waiting for Cladribine to be approved in 2010.