first i am not a doctor, so don't consider me as THE adviser
The first time i heard about it was when it was firtst withdrawn. My neuro told me that a great treatment would no more be soon available.
Then last year, in April 2006 i was in the middle of a tough crisis which let me time to spot on the web. i found out it was about to be back on the market (info on thisisms.com).
so i followed then the progress of its new launch, checking the FDA reports, and also checking the reports of previous patients who had been so happy to get it and sad to no more get it.
Also since my Rebif efficiency was decreasing: i had 3 crisis in a few months , when before it was once per two years, i was waiting for something new(and more important efficient). I was also aware of its risks, minimal considering the 2 dead people were taking Avonex and 2 amongst 3OOO, is not that bad.
But Tysabri was not yet available in France, so i had to wait still a few months.
After 6 months of Copax(my neuro had to make try another treatment before giving me Tysa) i had a new MRI that showed 20 lesions vs 4 before, which made i was a tysa candidate.
My neuro explained me then the risks which i knew already: even before, i had wrote her a letter explaining i was aware of the risks but also remindining why i did need it.
Anyway, she had already said me before it was allowed"if you were my brother i'd give it to you straight away", so the last toward Tys was quite fast.
She gave me the information of Biogen reminding all what it implied.
And then for my first infusion, a nurse gave me the paper contained in each Tysa bottle box.
I hope my experience helps you a bit, although, i don't have any Tysabri bible but the websites some good information about
when you type tysabri, you can find some conferences and other patients stories
and of course thisisms.com
So good luck and excuse my French cause i am