Just some background. Diagnosed Nov 06, sensory issues, on copaxone Nov 06 to May 07. Second MRI in May showed that some of my leisons had cleared, but just as many had appeared. Although I had no disability I had over 25 enhancing/active leisons, which was of concern to the Specialist, in an - its only a matter of time before something happens way. The Copaxone did something, but the disease was clearly pushing forward. I chose Tysabri as it was offered and I had not been on any of the interferon drugs and figured I could always go back.
I had my first infusion June 07 and had no reactions, but also was not able to see any change in my conditions, other than that the sensory issues that had subsided in April had not returned. I had my 3rd MRI on 11/19, and my Drs appt on December 3rd, and the Dr said she was amazed. Not only do I not have any new leisons, but I have NO enhancing/active leisons. Also my leison count has dropped significantly.
I have read in many places that there is not necessarily a correlation between the number of leisons on an MRI and disability, and have to agree as if there was always a link I probably would have been significantly disabled. In another post by Msladyinca (Lauren), she said her Dr was happy because there wasn't any disease progression, and that is what Tysabri claims.... I have to believe it is working for me, because thus far my disease progression has been illustrated by a leision infested MRI - until NOW.
I was hoping the MRI would look the same as May - as not to be disappointed, and I am now speechless.
Thanks for listening.