This Is MS Multiple Sclerosis Community: Knowledge & Support

A MUST-SEE 3 minute video from Biogen and Elan, explaining exactly how Tysabri works graphically (a bit technical, but you know our community is not scared of science

http://homepage.mac.com/vincentmacaluso ... ring7.html

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Disclaimer: Any information you find on this site should not be considered medical advice. All decisions should be made with the consent of your doctor, otherwise you are at your own risk.

Dear AAron, That is my Dr. Dr Vincent Macaluso. He also has another video on how he was first dx'ed. Very encouraging. Here is the site

http://healingwell.healthology.com/heal ... /17356.htm

then click on "Physician heal thyself. A Doctor's battle with MS"

God bless
Linda

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Tysabri video on FDA site.

First Monoclonal Antibody Treatment for MS

FDA recently approved the first monoclonal antibody treatment for patients with relapsing forms of multiple sclerosis. The product, called Tysabri (natalizumab), is intended to reduce the frequency of clinical exacerbations of the disease. Tysabri is marketed by Biogen Idec and Elan Pharmaceuticals.

The product is given intravenously every four weeks in a physician's office.
Tysabri appears to work by targeting part of the underlying inflammatory process in MS by inhibiting adhesion molecules on the surface of leukocytes. It's believed that this interaction prevents immune cells from migrating into the brain, where they can cause damage.

The drug's approval was based on positive results after the first year of treatment in two randomized, double-blind clinical trials. In one of the trials, in which Tysabri was compared to a placebo, it reduced the frequency of relapses by 66 percent. The manufacturer will continue these trials for another year.

Serious but uncommon side effects included infections, severe or life threatening allergic reactions, depression, and gallbladder problems. Common adverse reactions were generally mild and included non-serious infections, headache, and fatigue.

http://www.accessdata.fda.gov/scripts/c ... ?show=36#1
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New Tysabri Video

Health Watch
Wednesday, February 9, 2005


New hope for the 400,000 Americans suffering from Multiple Sclerosis.

In today's Health Team 9 Health Watch, Bay News Nine's Dr. Steven Seltzer introduces us to a woman taking a new drug to fight the disease. The drug is called Tysabri. What it has done for her, might work for you or a loved one.


http://www.bn9.com/content/8/2005/2/9/70319.html
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A somewhat older, but interesting video.

http://nationalmssociety.org/nyn/more_c ... ideo1b.asx
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