The specific interferon-induced proteins and mechanisms by which Avonex exerts its effects in multiple sclerosis have not been fully defined.
Safety and efficacy of treatment with Avonex beyond 3 years is not known.
Arron wrote:why is someone with such a complicated and risk-prone medical history allowed to participate in a clinical trial of a potentially dangerous product? FIVE YEARS of treatment with azathioprine, a powerful transplant drug?!?
....I don't know just who makes the final decision on what patients get into some of these clinical trials....
Ok..........here I go, huh?
Ok.........just what WAS the criteria to meet for the Tysabri/Avonex trial?
Ages Eligible for Study: 18 Years - 50 Years, Genders Eligible for Study: Both
Male and female subjects between 18 and 50 years of age who have a diagnosis of relapsing remitting multiple sclerosis
who have been treated with Avonex for at least 12 months prior to study entry.
Ok......No comment. All I can say is how interesting!
Oh, I guess I'd have to also say "that's it?"
Hey, I've seen people be diagnosed and un-diagnosed with RRMS constantly! What are the determining factors that are to be used in order to adequately determine that clinical trial participants have RRMS in the first place in order to be eligible for this trial? Based on what or which particular test results or diagnostic criteria? Poser, McDonald, Schumacher's? LP, MRI only, diagnosis by exclusion, the doctor's "gut feeling", all of the above? ....
Users browsing this forum: No registered users