heya sandy, i had a look at the centrum product and there isn't enough info to assess it properly. none of the forms are listed, so it's hard to say if the amounts given are elemental or not, or whether the form is the best one.
for example i can't comment on the form of vit E provided, but it says 30 IU and those are likely to be either a synthetic or natural form of alpha tocopherol. supplementing just one of the E8 complex has been shown to disrupt natural distribution of vit E fractions, suppressing things like gamma tocopherol which has tumor suppressant action. so, whole food sources are best, and after that, natural source E8 complex with all 4 tocopherols and all 4 tocotrienols.
also D2 is ergocalciferol not cholecalciferol. it's plant vitamin D2 which your body has to convert into D3. vitamin D3 is more bioavailable to humans and has a better effect on your serum levels.
also when taking high dose d3 it should be balanced carefully with calcium, magnesium, and zinc. the amounts in the centrum product are negligible. (and that counts in general too, not just in relation to d3 - they might keep a perfectly healthy person topped up, but they can't get someone who's sick back on track). further, zinc needs to be balanced against copper. so if you take a zinc supplement ensure it has a little copper in the mix. personally, i take a daily 50mg zinc citrate pill. it delivers 15mg elemental zinc, and is balanced with 2mg copper.
if you choose a b12 supplement, see if you can find a sublingual one using methylcobalamin (rather than cyanocobalamin).
READ ME key info on nutrient targets - www.thisisms.com/ftopict-2489.html
my approach: no meds so far - just nutrient-dense anti-inflammatory whole foods, and supplements where needed
info: www.whfoods.com, www.nutritiondata.com