This Is MS Multiple Sclerosis Knowledge & Support Community

Pardon my lack of knowledge and / or understanding.

I read in many posts that this med or this supplement or this regimen proved an (example) 60% reduction on active (sometimes not?) lesions...

Well; the question is: is that the existing lesions reduced to 60% of what they were (which mathematically would make the lesions almost non-existent after 8 sessions) or that the non-subject would get the 40% of the new active lesions...

How on earth are those lesions reduction computed? if we take 100 peeps; and all of them get x-Anti-MS-X's drug and that 60% of them have no "more" active lesions than 100 peeps that take nothing; how can we deduct that 60% is the result? And that 'without' the 'reduction' factor ...?

In the first case; if the lesions were reduced; how can MS still exists? The subject then is merely myelin regeneration?

Can anybody explain or direct me to something that clearly explain that?

Thanks and sorry for the babbling

It depends if that sentence ends with "compared with placebo".

It should usually read "60% reduction in active lesions compared with placebo". So the group using the active medication has 60% less active lesions than the placebo group. i.e., if the placebo group had 100 active lesions, the active med group would have 40, making it 60% less active lesions than the placebo group.