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symptom pattern

Posted: Fri May 14, 2010 8:27 am
by sbr487
Folks,

Over the years I have seen that my symptoms tend to be almost cyclical.
Not only that, the symptoms ramp over a few days. The day after I have major issues, the symptoms subside and I fell "normal". This cycle continues

It has taken me 15 years to realize that once my symptoms peak, I will have a better day ahead ...

Just checking if any one has observed similar thing, although, going by CCSVI theory, everyone would have different reactions depending on the sensitivity of immune, stenosis etc.

Posted: Fri May 14, 2010 8:57 am
by scorpion
I don't see how symptoms that are cyclical would fit with the CCSVI model at all. If you have a blockage that have caused your "symptoms" it would seem the "symptoms" would not be relieved until the blocakage has been removed. A blockage anywhere in your body(heart, neck, kidney, etc,) would not wax and wane but instead would simpley get worse.

Posted: Fri May 14, 2010 9:45 am
by sbr487
scorpion wrote:I don't see how symptoms that are cyclical would fit with the CCSVI model at all. If you have a blockage that have caused your "symptoms" it would seem the "symptoms" would not be relieved until the blocakage has been removed. A blockage anywhere in your body(heart, neck, kidney, etc,) would not wax and wane but instead would simpley get worse.
Are you really expecting a response?
Anyway, the symptoms would be severe when immune is actively cleaning up (which means inflammation). My fatigue is present all the time as is the reduced blood flow. The iron needs to build up in order to be recognized by immune system (they need a threshold level to get activated). In the current state of my MS, I do feel that immune gets activated and then withdraws once its work is done, only to be activated again ... see the cycle ...

Posted: Fri May 14, 2010 10:19 am
by scorpion
But MS stirkes more women than men. Women tend to struggle to get enough iron in their bodies prior to menapuase but yet they are more at risk for "iron buildup" than men? Yes I am really expecting an explanation. Actually I was hoping for a discussion but an explanation is cool.

Posted: Fri May 14, 2010 10:31 am
by sbr487
scorpion wrote:But MS stirkes more women than men. Women tend to struggle to get enough iron in their bodies prior to menapuase but yet they are more at risk for "iron buildup" than men? Yes I am really expecting an explanation. Actually I was hoping for a discussion but an explanation is cool.
Who know the complete story. The bottom line is venous issue. Recent research seems to suggest that a defective gene is to blame. Maybe females are more disposed than men. BTW, I dont understand how iron build up in brain is linked to iron deficiency. You have venous insufficiency, you end up accumulating iron anyway.

Posted: Fri May 14, 2010 10:36 am
by scorpion
If I am correct the "inflamation process" begins, according to you, due to excess iron in the brain. My question is if women have lower levels of iron than men, why would they be more at risk to delop MS? Wouldn't men, who have higher levels of iron, be more predisposed to develop MS?

Posted: Fri May 14, 2010 10:58 am
by sbr487
scorpion wrote:If I am correct the "inflamation process" begins, according to you, due to excess iron in the brain. My question is if women have lower levels of iron than men, why would they be more at risk to delop MS? Wouldn't men, who have higher levels of iron, be more predisposed to develop MS?
Incorrect. Venous insufficiency determines iron build up not iron per-se.
Similarly high levels of iron in normal persons would not result in MS.