Thyroid and MS
Posted: Fri May 06, 2005 5:24 pm
Wondering if any of you have experienced thyroid issues or even been tested for them.
I recently found out that hypothyroidism runs on both sides of my family--brother, maternal aunt, mother, maternal great aunt, and now, paternal grandfather. I got curious and looked up thyroid and MS on the web and found this study, Prevalence of autoimmune thyroiditis and non-immune thyroid disease in multiple sclerosis:
http://www.ncbi.nlm.nih.gov/entrez/quer ... t=Abstract
I just did a massive panel of labs tests today, including thyroid. Will let y'all know.
Interestingly, Campath-1H caused autoimmune hypothyroidism in 30% of the patients using it:
http://www.mult-sclerosis.org/Campath1H.html
This is also interesting...and important...for those of you on interferon:
Long-term follow-up of 106 multiple sclerosis patients undergoing IFN- 1a or 1b therapy: predictive factors of thyroid disease development and duration
http://jcem.endojournals.org/cgi/conten ... 004-2326v1
An excerpt: "Baseline thyroid autoimmunity was detected in 8.5% of patients and hypothyroidism in 2.8%. Thyroid dysfunction (80% hypothyroidism, 92% subclinical, 56% transient) developed in 24% (68% with autoimmunity) of patients and autoimmunity in 22.7% (45.5% with dysfunction), without significant differences between the two cytokines; 68% of dysfunctions occurred within the first year."
I recently found out that hypothyroidism runs on both sides of my family--brother, maternal aunt, mother, maternal great aunt, and now, paternal grandfather. I got curious and looked up thyroid and MS on the web and found this study, Prevalence of autoimmune thyroiditis and non-immune thyroid disease in multiple sclerosis:
http://www.ncbi.nlm.nih.gov/entrez/quer ... t=Abstract
I just did a massive panel of labs tests today, including thyroid. Will let y'all know.
Interestingly, Campath-1H caused autoimmune hypothyroidism in 30% of the patients using it:
http://www.mult-sclerosis.org/Campath1H.html
This is also interesting...and important...for those of you on interferon:
Long-term follow-up of 106 multiple sclerosis patients undergoing IFN- 1a or 1b therapy: predictive factors of thyroid disease development and duration
http://jcem.endojournals.org/cgi/conten ... 004-2326v1
An excerpt: "Baseline thyroid autoimmunity was detected in 8.5% of patients and hypothyroidism in 2.8%. Thyroid dysfunction (80% hypothyroidism, 92% subclinical, 56% transient) developed in 24% (68% with autoimmunity) of patients and autoimmunity in 22.7% (45.5% with dysfunction), without significant differences between the two cytokines; 68% of dysfunctions occurred within the first year."