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Anyone tried Citicoline (CDP-Choline)
Posted: Tue Jun 01, 2010 5:37 pm
by Frank
Its available as a supplement and has neuroprotective and neurotrophic properties and is widely uses for ischemic stroke in Europe. It is said (after encouraging preliminary results there is a phase-III trial running now) that stroke patients treated with Citicoline have a better outcome regarding sustained disability.
In terms of MS I only found a patent from 2004 that combines Citicoline with steroids, but no published data on MS.
Has anyone tried it for MS? Any thoughts on that drug?
--Frank
Re: Anyone tried Citicoline (CDP-Choline)
Posted: Sun Nov 27, 2011 8:29 am
by ikulo
Just wanted to bump this to see if anyone has had any experience with this yet.
Re: Anyone tried Citicoline (CDP-Choline)
Posted: Mon Nov 28, 2011 5:14 am
by NHE
I have no experience with citicoline. However, here's a freely available review paper on it (although it is a few years old now).
http://ntp.neuroscience.wisc.edu/facult ... atla80.pdf
The paper's abstract states that citicoline is thought to increase the biosynthesis of phosphatidylcholine.
NHE
Re: Anyone tried Citicoline (CDP-Choline)
Posted: Mon Nov 28, 2011 6:07 am
by NHE
Here are some additional papers from the same author.
CDP-choline Significantly Restores Phosphatidylcholine Levels by Differentially Affecting Phospholipase A2 and CTP: Phosphocholine Cytidylyltransferase after Stroke
http://ntp.neuroscience.wisc.edu/facult ... tla281.pdf
Cytidine 5 0 -Diphosphocholine (CDP-Choline)in Stroke and Other CNS Disorders.
http://ntp.neuroscience.wisc.edu/facult ... atla30.pdf
More papers from this author are available from the following link.
http://ntp.neuroscience.wisc.edu/faculty/adibhatla.html
NHE
Re: Anyone tried Citicoline (CDP-Choline)
Posted: Wed Dec 07, 2011 9:00 pm
by ikulo
Thanks for the info, NHE! Will check that out.