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Lamotrigine ineffective in secondary progressive MS

Posted: Wed Jul 14, 2010 4:46 am
by MSUK
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Abstract
BACKGROUND: Partial blockade of voltage-gated sodium channels is neuroprotective in experimental models of inflammatory demyelinating disease. In this phase 2 trial, we aimed to assess whether the sodium-channel blocker lamotrigine is also neuroprotective in patients with secondary progressive multiple sclerosis.... Read More - http://www.msrc.co.uk/index.cfm/fuseact ... ageid/1397